13 citations
,
December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
12 citations
,
July 2011 in “Experimental Dermatology” The ethosomal delivery system improves topical drug delivery and promotes hair growth.
380 citations
,
March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
68 citations
,
March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
11 citations
,
September 2012 in “Journal of Nanjing Medical University” Cyclosporine A was found to increase hair growth in mouse whisker follicles.
August 2025 in “Plastic and Aesthetic Research” Microneedling can effectively treat hair loss and works well with other treatments, but more research is needed.
October 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Root hair growth slows under force, confirming a model of cell wall mechanics.
19 citations
,
February 2001 in “Journal of paediatrics and child health” A new mutation in the mitochondrial DNA was found in a boy with MELAS, even though his family didn't show typical signs.
16 citations
,
September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
1 citations
,
July 2020 in “Journal of Biomedical Translational Research” Raccoon dogs can adapt well to life with three legs after forelimb amputation.
22 citations
,
July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
January 2009 in “Journal of the American Academy of Dermatology” Generalized trichoepitheliomas with alopecia may indicate myasthenia gravis.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
April 2025 in “Experimental Eye Research” The Oat mouse model shows mild retinal degeneration, useful for testing treatments.
October 2025 in “Phytochemistry Letters” 9 citations
,
February 2025 in “Journal of Nanobiotechnology” Biomimetic nanovesicles can speed up diabetic wound healing by regulating immune cell behavior and metabolism.
39 citations
,
April 2012 in “Journal of controlled release” New method uses hair follicles to deliver drugs deep into the skin.
70 citations
,
November 2020 in “The Ocular Surface” Organoids and organ chips can improve eye disease research and treatment.
September 1999 in “Molecular Carcinogenesis” Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.
75 citations
,
October 1999 in “Differentiation” Mouse keratin 6 isoforms have different expression patterns in various tissues.
8 citations
,
October 2021 in “Experimental cell research” Engineered vesicles from macrophages help hair growth in mice and humans.
8 citations
,
October 2024 in “Developmental Cell”
The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.
73 citations
,
November 2000 in “Proceedings of the National Academy of Sciences of the United States of America” There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
1 citations
,
January 2024 in “Animal Research and One Health” Mouse models are essential for studying and improving genetic traits in agriculture.
December 2025 in “eScience” A wireless, battery-free system uses Wi-Fi signals to enhance wound healing and enable smart healthcare at home.
4 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.
January 2019 in “Durham e-Theses (Durham University)” Less stiff collagen promotes higher cell growth in hair follicles.