85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
77 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
73 citations
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March 2010 in “Food and Chemical Toxicology” Zizyphus jujuba essential oil can promote hair growth.
70 citations
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July 2020 in “Pharmacological Reports” Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
68 citations
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November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
62 citations
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April 2008 in “Neurobiology of aging” Scientists found a gene in mice that causes early hearing loss.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
60 citations
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April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
60 citations
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August 2008 in “Human molecular genetics online/Human molecular genetics” A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
56 citations
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July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
44 citations
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October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
38 citations
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July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
38 citations
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September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
37 citations
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December 2024 in “Theranostics” The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
28 citations
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August 2015 in “Journal of functional biomaterials” Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
28 citations
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October 2004 in “Differentiation” A gene deletion causes the "hairless" trait in Iffa Credo rats.
24 citations
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November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
24 citations
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October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
19 citations
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August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
17 citations
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September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
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January 2019 in “International journal of biological sciences” Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
16 citations
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January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
15 citations
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June 2011 in “Journal of Ginseng Research” Korean Red Ginseng may improve skin condition and reduce allergy markers in atopic dermatitis patients.
14 citations
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January 2018 in “Scientific reports” Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
13 citations
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November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
13 citations
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May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
12 citations
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August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
11 citations
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March 2020 in “American Journal of Medical Genetics Part A” A mutation in the EDNRA gene causes Oro-Oto-Cardiac syndrome, affecting face and heart development.
11 citations
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July 2016 in “Current Opinion in Cell Biology” New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.