35 citations
,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
23 citations
,
May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
9 citations
,
December 2020 in “International Journal of Medical Sciences” iPSCs help understand and treat neurodevelopmental disorders.
42 citations
,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse skin glands need healthy nerves to grow properly during hair growth phases.
1 citations
,
March 2019 in “International Journal of Molecular Medicine” Mouse hair follicle cells can become heart-like cells without genetic changes.
2 citations
,
September 2017 in “Biotechniques/BioTechniques” Researchers created a mouse cell line to study hair growth and test hair growth drugs.
37 citations
,
December 2018 in “Frontiers in Immunology” Biodegradable microparticles help wounds heal without scars.
33 citations
,
December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
130 citations
,
February 2005 in “Proceedings of the National Academy of Sciences” Corneal cells can transform into skin and hair cells through specific signals.
4 citations
,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
January 2024 in “ACS Biomaterials Science & Engineering” A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
51 citations
,
April 2013 in “Journal of Investigative Dermatology” Hair follicle stem cells rely on nearby blood vessels for their maintenance and function.
55 citations
,
March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
561 citations
,
April 2003 in “Journal of Investigative Dermatology” CD34 is a marker for isolating stem-like cells in mouse hair follicles.
33 citations
,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
308 citations
,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
87 citations
,
September 2019 in “Nature Communications” SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
15 citations
,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
180 citations
,
January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
17 citations
,
January 2023 in “Frontiers in Cell and Developmental Biology” iPSCs are promising for studying and treating COVID-19.
39 citations
,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
8 citations
,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
March 2024 in “Bioactive Materials” New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
January 2013 in “edoc (University of Basel)” TRF1 is crucial for creating and maintaining stem cells and marks both pluripotent and adult stem cells.
3 citations
,
July 2022 in “Stem Cell Research & Therapy” Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
August 2025 in “BMC Research Notes” iPSC lines from different tissues share a common miRNA profile, supporting their pluripotent nature.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.