Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
11 citations
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January 2014 in “CellBio” Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.
39 citations
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January 2013 in “Journal of Investigative Dermatology” Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
5 citations
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March 2022 in “STAR Protocols” The method helps study hair follicle stem cells and calcium signals in mouse skin.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
153 citations
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April 1998 in “Current Biology” The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Hemoglobin α acts as an antioxidant in skin cells, especially protecting hair follicle stem cells from UV damage.
24 citations
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October 2010 in “Tissue Engineering Part A” Tissue-engineered skin can support hair growth after grafting, especially with mouse-derived dermis.
October 2014 in “Cancer research” Blocking mTORC1 reduces skin tumor growth in mice.
124 citations
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July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
41 citations
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July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
37 citations
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February 2007 in “Experimental Dermatology” Increasing PDCD4 protein may help prevent or treat some skin cancers.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
201 citations
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May 2001 in “Proceedings of the National Academy of Sciences” Overexpression of COX-2 in mice skin causes abnormal skin and hair development.
59 citations
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June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
19 citations
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December 2021 in “Stem Cell Research & Therapy” Muse cells from human bone marrow help reduce symptoms of atopic dermatitis in mice.
6 citations
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April 1993 in “Journal of Dermatological Science” Certain substances can strongly inhibit DNA synthesis in hair cells.
1 citations
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May 2023 in “PubMed” A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
31 citations
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October 2019 in “Genes & Diseases” Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
7 citations
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February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
1 citations
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August 2004 in “Journal of Investigative Dermatology Symposium Proceedings” Adult somatic stem cells could be used for future skin therapies.
August 2016 in “Journal of Investigative Dermatology” EZH2 is essential for hair growth and skin cell development.
January 2012 in “Springer eBooks” The skin has different types of stem cells that can repair and regenerate tissue.
5 citations
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January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
1 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The research mapped out the cell types and molecular processes involved in developing Cashmere goat hair follicles.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
STAT5 and Sox18 are crucial for hair growth and wound healing.