60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
53 citations
,
October 2003 in “Developmental Biology” Too much Sonic Hedgehog protein stops hair growth in embryos.
49 citations
,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
47 citations
,
June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
27 citations
,
May 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b is important for starting hair growth and developing hair follicles.
25 citations
,
November 2020 in “Proceedings of the National Academy of Sciences” HoxC genes are crucial for normal hair and nail development.
21 citations
,
December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
20 citations
,
February 2018 in “Cell transplantation” Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.
18 citations
,
November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
17 citations
,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
13 citations
,
March 2021 in “British Journal of Pharmacology” KY19382 helps regrow hair and create new hair follicles.
12 citations
,
October 2020 in “Scientific Reports” Necrostatin-1s can promote hair growth and may help treat hair loss.
11 citations
,
May 2022 in “Chinese medicine” Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
8 citations
,
January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
7 citations
,
January 2019 in “PeerJ” A protein called sFRP4 can slow down hair regrowth.
7 citations
,
March 2007 in “International Journal of Dermatology” Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
6 citations
,
September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
5 citations
,
October 2021 in “Signal Transduction and Targeted Therapy” Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
4 citations
,
January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
2 citations
,
May 2023 in “Veterinary Pathology” Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.
1 citations
,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
1 citations
,
March 2015 in “Journal of Visualized Experiments” Researchers developed a new, precise method to measure hair loss in mice using image analysis.
February 2026 in “ACS Biomaterials Science & Engineering” Human stem cells can help grow hair for regenerative medicine.
May 2025 in “International Journal of Molecular Sciences” DHHB from Platycladus orientalis L. promotes hair growth and could be a natural alternative to current treatments.
Platelet-derived extracellular vesicles can boost hair growth by activating a specific signaling pathway.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
September 2022 in “F1000Research” Removing hair from mice without reproductive glands led to grey hair, possibly helping to understand greying in aging.
Hedgehog signaling can create new hair follicles in adult skin but may increase cancer risk.