research A New Role of Non-Sex Hormone in the Pathogenesis of Female Pattern Hair Loss
Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.
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research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Effect of Marine-Derived Saccharides on Human Skin Fibroblasts and Dermal Papilla Cells
Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
research Anti-Hair Loss Effect of Adenosine Is Exerted by cAMP Mediated Wnt/β-Catenin Pathway Stimulation via Modulation of Gsk3β Activity in Cultured Human Dermal Papilla Cells
Adenosine can help treat hair loss by promoting hair growth.
research Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.
research Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia
Mutations in the HOXC13 gene cause hair and nail development issues.
research Minoxidil
Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect
Minoxidil boosts hair growth by activating PGHS-1.
research Mutations in Sterol O-Acyltransferase 1 (Soat1) Result in Hair Interior Defects in AKR/J Mice
A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages
Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
research Topographical and developmental studies on target sites of 1,25 (OH2) vitamin D3 in skin
Vitamin D3 affects cell differentiation in specific skin areas.
research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat
A gene deletion causes the "hairless" trait in Iffa Credo rats.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Improvement of androgenetic alopecia with topicalSophora flavescensAiton extract, and identification of the two active compounds in the extract that stimulate proliferation of human hair keratinocytes
Sophora flavescens extract helps hair growth and treats hair loss.
research A Review: Different Types of Plants and its Extract Use in Hair Loss and Hair Growth Therapy
Herbal treatments are effective and preferred for hair loss with fewer side effects.
research Effects of Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair Re-growth in Testosterone-treated Mice
Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
research Identification of the Rat Rex Mutation as a 7-bp Deletion at Splicing Acceptor Site of the Krt71 Gene
A gene mutation causes curly hair and hair loss in rats.
research Animal models of alopecia
The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Differentiation of Adipose Derived Stem Cells by Stimulating with Extracellular Vesicles Secreted from Dermal Papilla Cells Activated with Osteogenic and Adipogenic Inducers
Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.
research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro
EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
research Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice
Panax ginseng extract helps mice grow hair.
research Effects of dihydrotestosterone on rat dermal papilla cells in vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways
Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.
research Reviewer #1 (Public review): Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research The establishment and characterization of immortalized human dermal papilla cells and their hair growth promoting effects
Researchers made a cell line that grows quickly and can help with hair growth research.