97 citations
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January 1996 in “Clinical infectious diseases/Clinical infectious diseases (Online. University of Chicago. Press)” Fluconazole is somewhat effective for skin-related sporotrichosis but less so for severe forms, and should be a backup treatment.
September 2022 in “Journal of pharmaceutical sciences” Thicker minoxidil solutions work better and need less frequent application.
4 citations
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August 2023 in “Biomedicine & Pharmacotherapy” Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
Oral minoxidil affects prostate tissue but is less harmful than finasteride.
September 2025 in “Clinical Case Reports” Oral minoxidil can cause dry mouth, but switching to topical minoxidil may prevent this side effect.
Low-dose oral minoxidil can cause dry mouth.
2 citations
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May 2017 in “Zenodo (CERN European Organization for Nuclear Research)” Topical minoxidil 5% can cause erectile dysfunction and decreased libido.
3 citations
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April 2021 in “Journal of Cosmetic Dermatology” Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
48 citations
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June 1988 in “PubMed” Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
August 2025 in “Journal of Cosmetic Dermatology” Oral minoxidil users, especially for hypertension, may risk heart issues, and better monitoring guidelines are needed for alopecia patients.
17 citations
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May 1998 in “Contact Dermatitis” Minoxidil can cause pustular allergic reactions on skin.
2 citations
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September 2018 in “JAAD case reports” A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.
October 2024 in “Iraqi postgraduate medical journal” October 2025 in “Pharmaceuticals” Auranofin shows promise as a cancer treatment, especially when combined with other therapies.
1 citations
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March 2000 in “CRC Press eBooks” Flutamide helps with prostate cancer and some skin conditions but can harm the liver.
January 2009 in “Journal of Pakistan Association of Dermatology” Systemic cyproterone acetate and 5% topical minoxidil are effective and safe for treating female pattern hair loss.
18 citations
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February 2025 in “Drug Delivery and Translational Research” The microneedle patches effectively treat allergic conjunctivitis with controlled, sustained release of medication.
9 citations
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April 2006 in “International Journal of Dermatology” DFMO may help control hair growth and treat cancer.
2 citations
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November 2009 in “Korean journal of chemical engineering” Adding Brij 78 to minoxidil microparticles in a certain solution helps them stick to the skin better and prevents clumping.
24 citations
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January 2003 in “Drug Delivery” Minoxidil-containing vesicles improve hair growth.
November 2009 in “Eclética Química” The conclusion cannot be provided as the document content is not available.
3 citations
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May 1964 in “Nature” 3 citations
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March 2022 in “Archives of Dermatological Research”
86 citations
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July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
20 citations
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February 2017 in “European journal of pharmaceutical sciences” The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.
16 citations
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March 1981 in “PubMed” Minoxidil significantly lowers blood pressure in patients with hard-to-treat hypertension, but can cause fluid retention and excessive hair growth.
January 2026 in “Revista Colombiana de Ciencias Químico Farmacéuticas” Combining Minoxidil and finasteride is more effective for hair growth but may cause side effects.
7 citations
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June 2021 in “Cureus” Minoxidil can cause severe body swelling and fluid buildup, which improves after stopping the drug and using diuretics.