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September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
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May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
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October 2021 in “Scientific Reports” NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.
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September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
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February 2012 in “British Journal of Dermatology” Mutations in the p63 gene affect skin adhesion, barrier integrity, and hair growth.
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June 2007 in “Pharmacology Biochemistry and Behavior” Blocking progesterone metabolism can cause depression-like behavior in mice.
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January 2015 in “Development” Hoxc8 gene helps start mammary gland development by controlling specific signals.
August 2021 in “Journal of Investigative Dermatology” Platelet-rich plasma (PRP) helps regrow hair in male pattern baldness.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” LIPH mutations cause woolly hair in some Chinese people.
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August 2014 in “Toxicologic pathology” Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
January 2024 in “Circulation” Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
November 2022 in “Gigascience” A specific genetic deletion in goats affects cashmere yield and thickness.
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December 2014 in “Experimental Dermatology” Wnt5a overexpression alone doesn't cause psoriasis in mice but affects hair growth.
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July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
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March 2024 in “Journal of Neuroendocrinology” Reduced neurosteroid production increases fear in mice, suggesting potential PTSD treatments.
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May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
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December 2011 in “Canadian Journal of Microbiology” Serotype 4 of Ureaplasma showed the highest pathogenicity in female mice.
September 1990 in “Journal of Dermatological Science” January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
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December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
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February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
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September 2006 in “PLoS Genetics” The Apc gene is crucial for normal skin and thymus development.
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January 2019 in “Annals of dermatology/Annals of Dermatology” STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.