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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Overexpression of COX-2 in mice skin causes abnormal skin and hair development.

RXRα is crucial for hair growth and skin cell function.

Recognizing minor skin lesions can help identify serious cancer syndromes.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

The method effectively induces skin cancer in mice for studying tumor development.

Targeting SOX proteins may improve cancer treatment by restoring immune function.

MEX3A is crucial for maintaining intestinal stem cells in mice.

Mesenchymal MEIS2 is essential for whisker development without needing sensory nerves.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Microneedling and oral tranexamic acid both improve facial melasma, but microneedling shows more sustained benefits.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Connexin-26 gene mutations may increase cancer risk in KID syndrome patients.

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

The method effectively showed that the two exemestane preparations are bioequivalent.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

New mutations in the DSG4 gene cause a rare hair condition.

Ets2 gene is crucial for placental development in mice.

EPDS and MS might share an immune-related cause.

Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.

The device mimics human hair follicles and detects tiny forces and moments with high sensitivity.

Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.

Multiphoton microscopy effectively images mouse skin layers and structures.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.