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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

Testosterone makes XX skin more like male skin by changing its structure and cell makeup.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Adults with gender dysphoria on hormone treatment often have skin problems like acne, which are common but not always recognized.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Lip feminization is important for transgender women, requiring personalized approaches and expert consultation for best results.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.

Hormonal therapy in adults with gender dysphoria often leads to skin issues like acne, requiring a team of skin and hormone doctors.

Denying transgender minors gender-affirming care, while allowing it for cisgender minors, is sex discrimination.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Ciclosporin can cause excessive hair growth even with testosterone blockers.

Myoblast transplantation shows promise for treating various muscle and heart conditions.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

A specific protein in chicken embryos links early skin layers to feather development.

Minoxidil foam promotes hair growth and reduces hair loss safely in men.

Minoxidil foam effectively promotes hair growth and reduces hair loss in men.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.

The method effectively detects MeT and TP in dried blood spots after cream application.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

There is unequal access to gender-affirming surgeries in Canada, with a need for better coverage and specialized programs.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.