research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
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research Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers
Using a perfusion system and 3D spheroid culture improves the growth of corneal cell layers for tissue engineering.
research Clinical-exome sequencing unveils the genetic landscape of polycystic ovarian syndrome (PCOS) focusing on lean and obese phenotypes: implications for cost-effective diagnosis and personalized treatment
Early diagnosis and personalized treatment for PCOS are crucial, especially for young women in West Bengal, India.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients
Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration
Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
research The influence of CD26+ and CD26− fibroblasts on the regeneration of human dermo-epidermal skin substitutes
CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
research Recent Trends and Future Prospects of Phytosomes: A Concise Review
Phytosomes improve the body's absorption of plant extracts for better health benefits.
research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Wound Induced Hair Neogenesis – A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Role of umbilical cord mesenchymal stromal cells in skin rejuvenation
Umbilical cord cells may help delay skin aging.
research Epidermal growth factor, innovation and safety
Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
research Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair
Collagen XVII is important for skin aging and wound healing.
research Great Expectations: Induced pluripotent stem cell technologies in neurodevelopmental impairments
iPSCs help understand and treat neurodevelopmental disorders.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Skin cell-derived extracellular vesicles: a promising therapeutic strategy for cutaneous injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Effects of a gintonin-enriched fraction on hair growth: an in vitro and in vivo study
Gintonin-enriched fraction promotes hair growth and could be a potential alopecia treatment.
research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
research Rodent models in placental research. Implications for fetal origins of adult disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Cutaneous toxicities of new targeted cancer therapies: must know for diagnosis, management, and patient-proxy empowerment
New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
research Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos
Akt2 protein is essential for normal cell division in early mouse embryos.
research Keratin function and regulation in tissue homeostasis and pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.