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The conclusion is that substances can penetrate hair fibers through multiple pathways, including both the cell membrane complex and the non-keratinous parts.

New technologies show potential for better understanding and treating skin conditions with abnormal mucin, but more research is needed for clinical use.

New methods improve how well skin treatments work by helping drugs get through the skin barrier.

PEVs effectively deliver minoxidil through skin.

Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.

Follicular mucinosis causes significant damage to hair follicle cells.

Minoxidil foam enters hair follicles and skin for hair growth.

Alopecia mucinosa is a challenging condition with unclear diagnosis and treatment.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

A rare hair follicle tumor showed unusual high levels of mucin.

Alopecia mucinosa causes red, raised skin patches and hair loss.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

Some skin growths with mucin can form hair follicles and resemble skin cancer, but a special stain can help tell them apart.

Moderately lipophilic dyes penetrate skin deeply, while highly hydrophobic or lipophilic dyes stay on the surface.

Benign follicular mucinosis involves immune cells attacking hair follicles.

Gentamicin penetrates pig skin better through open hair follicles than blocked ones.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Iron oxide nanoparticles mainly enter the skin through hair follicles and sebocytes, not the dermis.

Silver nanoparticles can penetrate porcine skin up to about 15.6 μm, possibly through hair follicles.

Liposomes with certain properties can effectively deliver drugs deep into hair follicles.

A 29-year-old man had a jaw plaque diagnosed as follicular mucinosis, linked to nestin-positive hair follicle stem cells.

Nanoparticles don't penetrate intact skin but can enter through pores or damaged skin.

Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

Increased liposome fluidity boosts skin penetration of sodium fluorescein.

IPM enhances skin penetration of hydrophilic drugs.

A rare skin condition in children can look like other diseases.

PEVs improve minoxidil skin penetration, increasing hair growth.

Hair follicles are important for the absorption of certain drugs into the skin.