research Successful outcome of follicular unit extraction in a patient with alopecia due to Hansen’s disease
Follicular unit extraction successfully restored hair growth in a leprosy patient without disease relapse.
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690-720 / 1000+ results research Androgen Resistance Associated With a Qualitative Abnormality of the Androgen Receptor and Responsive to High Dose Androgen Therapy*
High-dose androgen therapy can help manage certain types of androgen resistance.
research In silico investigation of possible multi-target drugs against Glutamate S-transferase and prolyl tRNA synthetase in Onchocerca volvulus
Bedaquiline, Telmisartan, Diosmin, Azelastine, and Adapalene may be effective treatments for onchocerciasis.
research Fludalanine: Nice Try But No Hallelujah
Fludalanine failed as an effective oral antibiotic despite efforts.
research When two plus two must not equal four
Regulatory challenges make developing combination therapies in urology difficult and costly.
research Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy?
Targeting multiple pathways and understanding genetic mutations are crucial for effective melanoma therapy.
research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
[6]-Gingerdiol 3-monoacetate shows promise for treating T. whipplei infections.
research Combined drug triads for synergic neuroprotection in retinal degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Glucocorticoid Resistance Syndrome in 2 Patients With Diverse Genotype
Diagnosing and managing Glucocorticoid Resistance Syndrome is complex due to genetic differences and varied symptoms.
research Referee report. For: Drug utilization pattern and adverse drug reactions of chemotherapy in pediatric patients at Muhimbili National Hospital, Tanzania [version 1; peer review: 1 approved, 1 approved with reservations]
Most pediatric cancer patients at Muhimbili National Hospital experienced adverse drug reactions during chemotherapy, highlighting the need for careful monitoring.
research Spectrum and signals of medication-associated cognitive disorder: a comprehensive disproportionality analysis with cross-database validation
Many medications may be linked to cognitive disorders, but most lack warnings on labels.
research MULTIOMICS – A NEW EXCITING ERA OF RESEARCH
Multiomics is revolutionizing biology by enabling breakthroughs in research and disease diagnosis.
research N-methylformamide induces multiple organ toxicity in Fischer 344 rats
research Anti-MRSA malleable liposomes carrying chloramphenicol for ameliorating hair follicle targeting
DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.
research The human innate immune protein calprotectin elicits a multi-metal starvation response inPseudomonas aeruginosa
Calprotectin starves Pseudomonas aeruginosa of essential metals, affecting its growth and resistance.
research Efficacy and safety of dual-targeted therapy for refractory inflammatory bowel disease: a retrospective case series from three tertiary general hospitals in China
Dual-targeted therapy is effective and safe for difficult-to-treat inflammatory bowel disease.
research Genetic variants in AR and SHBG and resistance to hormonal castration in prostate cancer
Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.
research Anticancer drugs in surface waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity
New inhibitors may reduce gut toxicity from cancer drugs.
research Anti-invasive effects of minoxidil on human breast cancer cells: combination with ranolazine
Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.
research Primary cutaneous follicle center lymphoma presenting as frontal fibrosing alopecia
Biopsy is crucial for diagnosing unusual hair loss causes like lymphoma.
research Diseases of the skin. Drug ill effects on the skin.
All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.
research Drug Eruptions
Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.
research Treatment response to conventional and novel therapies in chronic prostatitis
Combining different treatments may be needed to effectively manage chronic prostatitis.
research 41261 Identification of Demographic and Clinical Features Associated with Multi-Biologic Failure in the CorEvitas Psoriasis Registry
Certain factors like being female, having high cholesterol, using Medicaid, and previous non-biologic treatments increase the risk of multiple biologic failures in psoriasis patients.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research ANTI-CANCER MEDICINS (CLASSIFICATION AND MECHANISMS OF ACTION)
Anti-cancer drugs are diverse and hard to classify due to their different forms and actions.
research Community-Acquired MRSA
CA-MRSA is a growing health issue needing new treatments and better hygiene to prevent spread.
research Pneumonitis Caused by Metronidazole
Metronidazole can cause lung disease.
research Phenotypic heterogeneity in human genetic diseases: ultrasensitivity-mediated threshold effects as a unifying molecular mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.