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MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.

Hair medullary cells in mammals vary in complexity, with humans having more structured cells similar to inner root sheath cells.

A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requires high doses of calcium and vitamin D for management.

NGAL may help maintain skin balance and is linked to skin disorders and cancers.

Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.

Trichocytic cytokeratins are found in hair, nails, tongue, and thymus cells, showing complex regulation in tissue development.

CD34⁺ cells help heal damaged limbs by promoting blood vessel growth.

RANK-RANKL signaling is essential for hair growth and skin health.

A man with alopecia universalis regrew hair temporarily after a bone treatment.

An elderly man with skin amyloidosis and abnormal blood proteins was monitored without finding widespread disease after 18 months.

Folliculotropic mycosis fungoides can affect the central nervous system in advanced stages.

SVpgC2a cells show abnormal growth and keratin changes, modeling early cancer development.

Pilomatrixoma involves abnormal hair keratin production and cell death, causing debris and cysts.

γδ T cells adapt uniquely to different tissues in mice.

Mast cells may significantly contribute to central centrifugal cicatricial alopecia.

The Oat mouse model shows mild retinal degeneration, useful for testing treatments.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

ILC1-like cells can cause alopecia areata by affecting hair follicles.

The rash resolved after stopping ponatinib.

Tongue cancer cells show more plectin-1 than non-cancer cells, but both have similar levels of trichohyalin.

Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.

Basonuclin helps keratinocytes multiply and prevents them from fully maturing.

The study suggests that a specific type of immune cell, memory-like NK cells, may increase during active hair loss in Alopecia areata.

Arg1+ macrophages may play a role in causing alopecia areata.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.