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Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

81 citations , September 2005 in “The American journal of pathology”

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

research Skin ageing

76 citations , May 2007 in “Menopause International”

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

research Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function

74 citations , June 2018 in “Cell death and disease”

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

research Regeneration of skin appendages and nerves: current status and further challenges

71 citations , February 2020 in “Journal of Translational Medicine”

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

research Skin aging: are adipocytes the next target?

70 citations , July 2016 in “Aging”

Targeting dermal adipocytes may help combat skin aging.

research Oestrogen functions in skin and skin appendages

68 citations , June 2005 in “Expert Opinion on Therapeutic Targets”

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research Emerging nonmetabolic functions of skin fat

65 citations , January 2018 in “Nature Reviews Endocrinology”

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

research The role of macrophages in skin homeostasis

65 citations , February 2017 in “Pflügers Archiv - European Journal of Physiology”

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration

56 citations , February 2012 in “Cell Cycle”

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

research Bacteria induce skin regeneration via IL-1β signaling

53 citations , April 2021 in “Cell Host & Microbe”

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense

49 citations , March 2019 in “Journal of Investigative Dermatology”

Skin fat plays a key role in immune defense and healing beyond just storing energy.

JunB Defines Functional And Structural Integrity Of The Epidermal-Pilosebaceous Unit In The Skin

research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin

48 citations , August 2018 in “Nature Communications”

JunB is crucial for maintaining healthy skin and hair follicles.

Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

research Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice

48 citations , May 2015 in “NPJ microgravity”

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin

48 citations , January 2000 in “Hormone Research in Paediatrics”

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

research Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases

47 citations , September 2023 in “Pharmacological Reports”

Vitamins A, B3, C, D, and E can improve skin health and immunity.

research Regulatory T cells in inflammatory skin disease: from mice to humans

43 citations , February 2019 in “International immunology”

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

research Deciphering the functions of the hair follicle infundibulum in skin physiology and disease

38 citations , September 2014 in “Cell and Tissue Research”

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

research In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles

32 citations , June 2017 in “Journal of Pharmaceutical Sciences”

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

research Stem cells and aberrant signaling of molecular systems in skin aging

25 citations , November 2014 in “Ageing Research Reviews”

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

research Stem Cells in Dermatology and Anti-aging Care of the Skin

23 citations , August 2018 in “Facial Plastic Surgery Clinics of North America”

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

research Getting under the skin of hair aging: the impact of the hair follicle environment

20 citations , May 2020 in “Experimental Dermatology”

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

research GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing

19 citations , January 2015 in “Scientific Reports”

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Effect of Red Clover Isoflavones on Skin, Appendages, and Mucosal Status in Postmenopausal Women

research Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women

19 citations , January 2011 in “Obstetrics and gynecology international”

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

18 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.