114 citations
,
March 2010 in “Zebrafish” PROTO1 and PROTO2 protect against hearing damage.
97 citations
,
March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause a severe form of brittle hair and skin issues.
86 citations
,
June 1998 in “Journal of Investigative Dermatology” The hairless gene mutation causes baldness by disrupting hair follicle structure.
79 citations
,
August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
63 citations
,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
55 citations
,
August 2012 in “Resources and Environment” Landfill leachate harms liver and kidneys in rats, posing health risks.
54 citations
,
May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
53 citations
,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
53 citations
,
January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
52 citations
,
January 2003 in “Journal of Investigative Dermatology” Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
51 citations
,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
50 citations
,
January 1986 46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
44 citations
,
November 2018 in “Journal of applied ecology” Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.
42 citations
,
January 2014 in “BMC Genomics” Cetaceans lost hair genes to adapt to water.
42 citations
,
June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
41 citations
,
October 2001 in “Experimental Dermatology” The nude gene is important for skin and hair development.
40 citations
,
August 2021 in “International Journal of Molecular Sciences” The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
39 citations
,
August 2017 in “Annual Review of Genetics” Understanding tissue regeneration in animals can improve regenerative medicine.
37 citations
,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
37 citations
,
January 2000 in “International Journal of Pharmaceutics” Topical treatments can regrow hair on bald scalps.
37 citations
,
July 1999 in “The EMBO Journal” Overexpression of certain genes can shorten hair by disrupting the hair-growth cycle.
36 citations
,
April 2022 in “Nutrients” Langsat fruit has health benefits like fighting malaria, bacteria, and aging, but its peel is toxic.
36 citations
,
August 2016 in “The Plant cell” A specific enzyme is crucial for the bean plant's relationship with certain beneficial soil bacteria and fungi.
34 citations
,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
33 citations
,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
29 citations
,
June 1998 in “Developmental Biology” More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
27 citations
,
February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
27 citations
,
November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.