68 citations
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September 2018 in “Trends in Cell Biology” Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
61 citations
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March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
59 citations
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March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
54 citations
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May 2018 in “International journal of risk & safety in medicine” Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.
52 citations
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October 2016 in “Clinics in Dermatology” Some medications can cause acne, and stopping these drugs is the main treatment.
50 citations
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March 2021 in “Journal of investigational allergology & clinical immunology” Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
50 citations
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May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
48 citations
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
48 citations
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June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
47 citations
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
47 citations
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June 2012 in “Genes & Development” A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
46 citations
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March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
46 citations
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September 2010 in “Southern Medical Journal” Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
44 citations
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
44 citations
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November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
41 citations
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December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
40 citations
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August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
40 citations
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September 2019 in “Molecular and Cellular Endocrinology” Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
40 citations
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July 2007 in “Dermatologic Therapy” Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
39 citations
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April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
39 citations
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October 2014 in “Schweizerische medizinische Wochenschrift” Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
38 citations
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December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
36 citations
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July 2020 in “Frontiers in Medicine” Spironolactone might help protect against severe lung problems in COVID-19 patients.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
35 citations
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May 2019 in “Frontiers in genetics” Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.
34 citations
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September 2020 in “BMC Endocrine Disorders” Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
33 citations
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October 2010 in “Journal of Dermatological Science” Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
32 citations
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August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.