154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
148 citations
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April 2009 in “Molecular Pharmaceutics” Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
130 citations
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November 2017 in “Frontiers in Immunology” The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
103 citations
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March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
98 citations
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August 2004 in “BJU international” Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
88 citations
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July 2014 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.
80 citations
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September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
67 citations
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May 2016 in “Journal of Cosmetic Dermatology” Peptides, proteins, and growth factors in skincare show promise for improving skin health.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
64 citations
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March 2021 in “Anaesthesia” Iron deficiency in women is common, often overlooked, and needs better recognition and treatment.
59 citations
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November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
58 citations
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January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
56 citations
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November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
42 citations
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September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
41 citations
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November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
40 citations
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July 2011 in “The journal of clinical hypertension” Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.
39 citations
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June 2018 in “Burns” The spiny mouse can fully regenerate skin after burns, unlike the lab mouse.
37 citations
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January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
35 citations
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May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
32 citations
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January 2006 in “Liver transplantation” Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
31 citations
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May 2018 in “Seminars in Plastic Surgery” An algorithm was created to simplify lip reconstruction after surgery.
29 citations
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December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
29 citations
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July 2008 in “British Journal of Dermatology” The patient had paraneoplastic pemphigus without mucosal involvement.
27 citations
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September 2015 in “PharmaNutrition” Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
26 citations
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December 2020 in “Cleveland Clinic Journal of Medicine” Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
26 citations
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March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
25 citations
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April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.