October 2023 in “Toxicology and Applied Pharmacology” Finasteride is more harmful to male reproductive health than minoxidil.
52 citations
,
September 2012 in “Oncogene”
May 2023 in “Health science reports” Coloring shampoos for gray hair may cause gene mutation, reproductive issues, and skin damage, needing stricter regulation and expert consultation.
January 2014 in “Dermatology Review” Folate may reduce methotrexate side effects in psoriasis patients, but its impact on effectiveness is unclear.
3 citations
,
April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
30 citations
,
January 2021 in “Journal of Clinical Immunology” FOXN1 mutations can cause varying immune and physical issues, with severity influenced by gene activity and possibly other factors.
14 citations
,
January 2014 in “Cells Tissues Organs” Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
October 2024 in “Journal of the Endocrine Society” Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
SLC24A5 shows a clear selective sweep, but no link to UV radiation intensity.
11 citations
,
March 2023 in “Marine Drugs” Compounds from Monascus purpureus showed mild antifungal effects.
26 citations
,
May 2024 in “Molecular Neurodegeneration” H1 increases risk for neurodegenerative diseases, while H2 offers protection but is linked to other disorders.
August 2023 in “Frontiers in Endocrinology” Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.
4 citations
,
August 2013 in “Chinese Medical Journal” A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.
7 citations
,
August 2017 in “Journal of dermatological science” Sorafenib causes skin reactions by increasing the number and activity of skin mast cells.
5 citations
,
May 1983 in “Australian journal of biological sciences” Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.
October 2020 in “Stem cells” The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
April 2016 in “Journal of Investigative Dermatology” MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
11 citations
,
November 2011 in “The Journal of Dermatology” Connexin-26 gene mutations may increase cancer risk in KID syndrome patients.
9 citations
,
March 1968 in “The BMJ” A woman's severe skin reaction was caused by an allergy to a skin treatment.
December 2025 in “Biomedicine & Pharmacotherapy” Melamax® protects skin from UV damage and reduces inflammation and oxidative stress.
Gene editing holds promise for skin treatments but needs careful safety and ethical consideration.
June 2015 in “OhioLink ETD Center (Ohio Library and Information Network)” UVB exposure affects retinoid metabolism, which is important for skin cancer progression and treatment.
November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
In vitro methods are crucial for developing effective and humane cosmetic ingredients.
4 citations
,
June 2002 in “Veterinary Dermatology” Prenatal retinoic acid exposure increased cell proliferation in mouse hair follicles without affecting their development.
8 citations
,
October 2023 in “Frontiers in Immunology” Certain cytokines may cause or be affected by immune skin diseases, suggesting possible new treatments.
September 2013 in “Helda (University of Helsinki)” Mutations in specific genes cause certain congenital defects in dogs, aiding in understanding similar human diseases.
32 citations
,
June 2012 in “PLoS ONE” Blocking IL-8 can reduce skin rashes from cancer treatment.
21 citations
,
February 2006 in “Clinical Cancer Research” Mitf plays a key role in melanoma progression and is linked to disease stage.
4 citations
,
March 2007 in “Annales de Dermatologie et de Vénéréologie” Hair care products can cause skin irritation and allergies due to certain chemicals.