research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene
SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.
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research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid LupusErythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
research MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Identification of Biomarkers in Affected Hair Follicles from Chronic Discoid Lupus Erythematosus by Weighted Gene Co-Expression Network Analysis
Key genes linked to immune response are highly active in lupus-affected hair follicles.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research A comparative study of skin transcriptomes and histological observations for black and white hair colors of giant panda
The study found that giant pandas have more melanin in black hair follicles than white, with gene expression differences that could affect hair color and skin health.
research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Tissue Repair Mechanisms of Dental Pulp Stem Cells: A Comprehensive Review from Cutaneous Regeneration to Mucosal Healing
Dental pulp stem cells can help heal skin and mucosal wounds effectively.
research Review of the 2024 American Academy of Dermatology (AAD) Annual Meeting
New treatments for skin conditions show promise, especially Coacillium® for hair growth in young people with alopecia areata.
research 301 Association between Hair Proliferation and Flavonoid Silibinin in Human Dermal Papilla Cells
Silibinin may help promote hair growth and treat hair loss.
research Alpinetin promotes hair regeneration via activating hair follicle stem cells
Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
Quiescent adult stem cells are crucial for tissue repair and maintenance.
research Molecular mechanisms of asymmetric divisions in mammary stem cells
Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
research Local and systemic mechanisms that control the hair follicle stem cell niche
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
AP-1 controls tumor cell type by affecting key signaling pathways.
research Regulation of stem cell function by protein ubiquitylation
Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
research The palette of techniques for cell cycle analysis
New techniques improve understanding of cell cycle dynamics at the single-cell level.
research Shikimic acid, a mannose bioisostere, promotes hair growth with the induction of anagen hair cycle
Shikimic acid promotes hair growth.
research Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hh Signaling Pathway
The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
research Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
research Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells
The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.
research Inflammatory auxo-action in the stem cell division theory of cancer
Chronic inflammation can cause cancer by making stem cells divide and mutate.
research Bone marrow-derived vasculogenesis leads to scarless regeneration in deep wounds with periosteal defects
Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Comparison between low-dose chemotherapy and surgery for the treatment of extremity-associated solitary bone lesions in children with Langerhans cell histiocytosis in South China: A case-control study
Low-dose chemotherapy is safer, more effective, and cost-effective than surgery for treating bone lesions in children.
research eLife Assessment: The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
research Peer Review #4 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)"
The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.
research Peer Review #1 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)"
The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.
research Peer Review #2 of "Inflammatory auxo-action in the stem cell division theory of cancer (v0.1)"
The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.