January 2021 in “Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)” N-Cadherin is crucial in scar formation, offering potential for scar prevention therapies.
288 citations
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January 2001 in “Journal of Biological Chemistry” Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
17 citations
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April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
April 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
2 citations
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January 2023 in “PubMed” Targeting FGF5 could help treat prostate cancer.
160 citations
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January 2017 in “Development” Blood vessels and specific genes help turn cartilage into bone when bones heal.
19 citations
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February 2008 in “Archives of Dermatological Research” Mast cells might contribute to hair loss by causing skin thickening.
Smad4 is crucial for muscle repair, especially in aging, by promoting cell growth over differentiation.
1 citations
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October 2025 γδ T cells help control tissue scarring and blood vessel growth in response to foreign objects.
63 citations
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September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
May 2022 in “Journal of Immunology” A parasite molecule can speed up skin healing and reduce scarring.
467 citations
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May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
81 citations
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November 2012 in “Journal of the National Cancer Institute” The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
July 2021 in “Plastic and reconstructive surgery. Global open” Verteporfin treatment in mice led to complete skin healing without scarring.
29 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.
January 2001 in “Chinese Journal of Reparative and Reconstructive Surgery” EGF aids skin development and healing, while bFGF absence in embryos may allow scar-free healing.
April 2026 in “Brazilian Journal of Hair Health” Perifollicular fibrosis hinders hair regrowth in androgenetic alopecia, and new treatments targeting fibrosis are needed.
January 2025 in “PLoS ONE” Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
3 citations
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May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” M2 macrophages help hair regrowth in wounds by making growth factors.
46 citations
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
50 citations
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December 2017 in “British Journal of Dermatology” Different skin cells produce unique materials, which can improve skin substitutes for healing.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
April 2019 in “Journal of Investigative Dermatology” Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
17 citations
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November 2015 in “Oxidative Medicine and Cellular Longevity” Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.
12 citations
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January 1991 in “Acta Dermato Venereologica” Basal cell epithelioma-like changes are most similar to normal basal cells.
July 2025 in “Journal of Investigative Dermatology” Laser treatment boosts hair growth by activating a key growth factor.
20 citations
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January 2017 in “Experimental Dermatology” Igf1r helps regulate hair growth cycles.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A parasite-derived molecule speeds up skin healing and affects immune cell behavior without increasing scarring.