research Emerging biomedical engineering strategies for hair follicle regeneration
New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
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research Gray Hair: From Preventive to Treatment
Gray hair can potentially be managed or reversed with treatments that boost melanin production and address nutritional deficiencies.
research ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling
ZO-1 helps hair follicle stem cells renew better by changing their structure.
research The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
research Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research Carbon, nitrogen, and sulfur elemental and isotopic variations in mouse hair and bone collagen during short-term graded calorie restriction
Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.
research Melanocytes in regenerative medicine applications and disease modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Developmental Mapping of Hair Follicles in the Embryonic Stages of Cashmere Goats Using Proteomic and Metabolomic Construction
Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.
research Proteomic Identification and Quantification of Secretory Proteins in Human Dermal Fibroblast-Conditioned Medium for Wound Repair and Hair Regeneration
The research found proteins in human skin cells that help with wound healing and hair growth, which could lead to new treatments.
research Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Activin A and follistatin control when ear hair cells form in mice.
research Decision letter: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
Activin A promotes ear hair cell development, while follistatin delays it.
research Oral Administration of TrkB Agonist, 7, 8–Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin–Induced Vestibular Injury in Guinea Pig
research Mesenchymal Stem Cells for Regenerative Medicine
Mesenchymal stem cells can help repair body tissues with low risk of rejection.
research The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Close Temporal Relationship between Oscillating Cytosolic K+ and Growth in Root Hairs of Arabidopsis
Potassium changes lead root hair growth, with calcium and other factors regulating the process.
research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat
Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
research Hub biomarkers in ultrasound-guided bladder cancer and osteosarcoma: Myosin light chain kinase and caldesmon
Lower levels of MYLK and CALD1 in bladder cancer and osteosarcoma are linked to worse survival rates.
research 090 Stromal re-organization in hair follicle development and cancer suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
research Comparative transcriptomic analysis of dermal wound healing reveals de novo skeletal muscle regeneration in Acomys cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Faculty Opinions recommendation of Dermal sheath contraction powers stem cell niche relocation during hair cycle regression.
The dermal sheath's contraction is crucial for hair follicle regression and stem cell relocation.
research Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane RemodelingIn Vivo
Actin filaments help stabilize and integrate cell membranes during transfer.
research Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.
Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
research Inhibitory effects of the ATP-sensitive potassium channel openers cromakalim, pinacidil and minoxidil on the carbachol–response curve in porcine detrusor muscle
Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
research Does myo-inositol oxygenase, the only enzyme to catalyze myo-inositol in vivo, play a role in the etiology of polycystic ovarian syndrome?
The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.
research Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Arginine Transferase Activity In Homogenates From Guinea-Pig Hair Follicles
research A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins
The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.