research Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia
AMT may cause hair loss and changing dWAT activity could help treat it.
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150-180 / 1000+ results research Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research Correlation of carotid intima media thickness and aortic stiffness index with androgenetic alopecia
Men with severe hair loss may have a higher risk of heart disease.
research Different phenotypes in a family with androgen insensitivity caused by the same M780I point mutation in the androgen receptor gene.
The same gene mutation can cause different symptoms in family members.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research The presence of insulin resistance and comparison of various insulin sensivity indices in women with androgenetic alopecia.
Women with androgenetic alopecia (AGA) are more insulin resistant than healthy women, with various insulin sensitivity indices being higher in the AGA group. An oral glucose tolerance test is suggested for women with AGA.
research Intermolecular NH 2 -/Carboxyl-terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.
research Normalized androgen ratio: its application to clinical dermatology
The normalized androgen ratio can help manage conditions with excess androgen activity in women.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research Free Androgen Index (FAI): Marker of Premature Androgenetic Alopecia in Men
The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
research Carotid Intima-Media thickness (C-IMT) in androgenic alopecia patient
Women with androgenic alopecia may have a higher risk of artery problems.
research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line
Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
research SUN-049 Male Pattern Baldness and Waist-Hip Ratio as Markers of Arterial Stiffness in Transgender Men Undergoing Long-Term Testosterone Therapy
Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
research Comparison of Components of Metabolic Syndrome in Androgenic Alopecia versus Healthy Population
People with androgenic alopecia are more likely to have metabolic syndrome than healthy individuals.
research TESTOSTERONE-INDUCED ANDROGENETIC ALOPECIA MICE MODEL: A PRELIMINARY STUDY
A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
research Late presentation of myotonic dystrophy
Myotonic dystrophy should be considered in patients with hair thinning, and genetic counseling is important.
research Dodatek A: Model matematyczny AL/RC/ASE. Functional Androgen Axis (FOA) - wersja operacyjna v1.2
The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.
research Dodatek A: Model matematyczny AL/RC/ASE. Functional Androgen Axis (FOA) - wersja operacyjna v1.2
The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.
research L-Ornithine ketoacid-transaminase assay in hair roots of homozygotes and heterozygotes for gyrate atrophy
research Anabolic-androgenic steroids. Mechanism of action and clinical effects
Anabolic-androgenic steroids are dangerous and educating people about their risks is essential.
research SAT-288 Successful Virilization of a PAIS Patient with a Missense Mutation In The Ligand-binding Domain Of The Androgen Receptor with Combined High-dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Risk of rhabdomyolysis from 5-α reductase inhibitors
Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.
research Androgens Induce Nongenomic Stimulation of Colonic Contractile Activity through Induction of Calcium Sensitization and Phosphorylation of LC20 and CPI-17
Androgens like testosterone increase colon muscle contractions by affecting calcium pathways.
research EXPRESS: Free androgen index and its relation with female pattern hair loss
FAI is a better marker for predicting female hair loss than testosterone or SHBG alone.
research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome
A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.
research Self-assembling peptide inspired by insulin and type 1 insulin-like growth factor for the treatment of androgenetic alopecia
Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
research Atherogenic index of plasma in non-obese women with androgenetic alopecia
Non-obese women with hair loss have higher heart disease risk.
research Evaluation of dry eye parameters and meibomian gland function using the Lipiscan system in male androgenetic alopecia patients
Men with androgenetic alopecia may have more severe dry eye and meibomian gland dysfunction.
research Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.