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NAD⁺ Biology in Aging and Chronic Disease: Mechanisms and Evidence Across Skin, Fertility, Osteoarthritis, Hearing and Vision Loss, Gut Health, Cardiovascular-Hepatic Metabolism, Neurological Disorders, and Muscle

research NAD⁺ Biology in Ageing and Chronic Disease: Mechanisms and Evidence across Skin, Fertility, Osteoarthritis, Hearing and Vision Loss, Gut Health, Cardiovascular–Hepatic Metabolism, Neurological Disorders, and Muscle

January 2026 in “Annals of Clinical Endocrinology and Metabolism”

Restoring NAD⁺ may help with aging and chronic diseases, but more research is needed.

research Nerve growth factor regulates the proliferation of cashmere goat outer root sheath cells through the activation of cAMP-binding protein

1 citations , July 2019 in “Small ruminant research”

Nerve growth factor helps cashmere goat hair cells grow by activating a specific protein.

research Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase

April 2025

ACA from Alpinia galanga may prevent testosterone-related hair loss.

research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas

2 citations , March 2019 in “Journal of Histochemistry and Cytochemistry”

Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.

research Nelfb promotes dermal white adipose tissue formation through RNA Polymerase II mediated adipogenic gene regulation

September 2025 in “Development”

Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.

research The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin‐1 (PN‐1) inhibition

14 citations , August 2014 in “The FASEB Journal”

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

research Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene

January 2022 in “Mammalian Genome”

The wavy coat in NCT mice is caused by multiple genes, including a mutation in the Prss53 gene.

research The Arabidopsis Receptor-like Kinase CAP1 Promotes Shoot Growth under Ammonium Stress

5 citations , October 2022 in “Biology”

CAP1 helps Arabidopsis plants grow better under ammonium stress.

N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

research N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats

2 citations , November 2022 in “Animal Bioscience”

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

research Sequence Analysis of mtDNA NADH-Ubiquinone Oxidoreductase Chain 1 Gene (ND1) of the Asian Black Bear Sichuan Subspecies (Ursus thibetanus mupinensis)

January 2007 in “Journal of Southwest University”

The ND1 gene of the Asian black bear Sichuan subspecies is similar to other bear species.

LncRNA-PCAT1 Maintains Characteristics of Dermal Papilla Cells and Promotes Hair Follicle Regeneration by Regulating miR-329/Wnt10b Axis

research LncRNA-PCAT1 maintains characteristics of dermal papilla cells and promotes hair follicle regeneration by regulating miR-329/Wnt10b axis

13 citations , April 2020 in “Experimental Cell Research”

PCAT1 helps hair growth by controlling miR-329/Wnt10b.

research A HPLC-Based Chloramphenicol Acetyltransferase Assay for Assessing Hair Growth: Comparison of the Sensitivity of UV and Fluorescence Detection

4 citations , January 1993 in “Clinical Chemistry and Laboratory Medicine (CCLM)”

The new method is 1000 times more sensitive for measuring hair growth.

research AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

17 citations , February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Elucidating the Roles of Three β-Glucuronosyltransferases Acting on Arabinogalactan-Proteins Using a CRISPR-Cas9 Multiplexing Approach in Arabidopsis

research Elucidating the roles of three β-glucuronosyltransferases (GLCATs) acting on arabinogalactan-proteins using a CRISPR-Cas9 multiplexing approach in Arabidopsis

28 citations , May 2020 in “BMC plant biology”

The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.

research A novel eco-friendly Acinetobacter strain A1-4-2 for bioremediation of aquatic pollutants

2 citations , July 2025 in “Scientific Reports”

Acinetobacter strain A1-4-2 can safely clean water pollutants.

research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles

34 citations , October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle

January 2007

research Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 induces proliferation of CD34+ hair follicle stem cell

January 2017 in “Seoul National University Open Repository (Seoul National University)”

AIMP1 can boost hair growth by increasing stem cell activity.

research Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid‐treated culture of a newborn rat keratinocyte cell line

39 citations , August 1998 in “FEBS Letters”

Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

research Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice

February 2024 in “Journal of Investigative Dermatology”

Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.

research N6-methyladenosine (m6A)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter

2 citations , August 2024 in “Animal Bioscience”

m6A-circHECA may affect cashmere goat hair growth and is possibly controlled by gene promoter methylation.

research ENDOXAN ALOPECIA

21 citations , August 1960 in “British journal of dermatology/British journal of dermatology, Supplement”

Endoxan often causes hair loss, which usually starts in the third week of treatment.

research Expression of Wnt Genes in Echinaster Sepositus Arm Regeneration

2 citations , January 2018 in “International Journal of Biochemistry & Physiology”

Wnt genes help starfish regrow arms by aiding wound healing and cell development.

Development of an Exfoliating Dermocosmetic Formulation with Babassu Fibers to Aid in the Treatment of Androgenetic Alopecia

research DEVELOPMENT OF AN EXFOLIATING DERMOCOSMETIC FORMULATION WITH BABASSU FIBERS TO HELP ON THE TREATMENT OF ANDROGENETIC ALOPECIA

July 2024 in “Revista Científica de Estética e Cosmetologia”

The babassu fiber exfoliating product for hair loss should be stored in a cool place to stay effective.

research Pomegranate Powerhouse : A Synthesis of Scientific Insights into Its Nutraceutical Marvels and Biomedical Applications

February 2024 in “International Journal of Scientific Research in Science and Technology”

Pomegranates have many health benefits, including fighting bacteria, viruses, cancer, and diabetes.

A Success Story of Cerebral Arteriovenous Malformation Treated with Stereotactic Radiosurgery in Bangladesh

research A Success Story of Cerebral Arteriovenous Malformation (AVM) Treated with Stereotactic Radiosurgery (SRS) in Bangladesh

September 2023 in “Bangladesh Journal of Neurosurgery”

Stereotactic Radiosurgery is an effective non-invasive treatment for cerebral AVM, with successful outcomes and minimal side effects.

Possible Contributory and Protective Factors in Medication Associated Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System

research 0557 Possible Contributory and Protective Factors in Medication Associated Obstructive Sleep Apnea (OSA): Results from the US Food and Drug Administration (FDA) Adverse Events Reporting System (FAERS)

April 2020 in “Sleep”

Some drugs may increase the risk of obstructive sleep apnea, while others like certain biologics might decrease it.

research Evaluation of the relationship between androgenetic alopecia and blood groups and Rhesus factor

August 2020 in “International Journal of Clinical Practice”

No link between hair loss and blood groups or Rhesus factor.

research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning

January 2017 in “Brazilian Journal of Pharmaceutical Sciences”

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

research Amphetamine and N-Acetylamphetamine Incorporation into Hair: An Investigation of the Potential Role of Drug Basicity in Hair Color Bias*

65 citations , May 2001 in “Journal of Analytical Toxicology”

Basic drugs like amphetamine are absorbed more in darker hair than lighter hair.

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