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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Blocking CISD1 reduces hearing loss from cisplatin in mice.

Silver oxide nanoparticles help detect small molecules effectively.

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

A new device mimics hair follicle functions and detects tiny forces with high sensitivity.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Transethosomal gels improve naftifine skin delivery better than Exoderil cream.

The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.

Microneedle Therapy System effectively treats acne, scars, and hair loss safely.

Reducing reactive oxygen species can help treat nerve damage from platinum cancer drugs.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

New technologies replicate human skin for testing without animals.

Light-activated hyaluronic acid derivatives can enhance skin healing and regeneration.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Noncoding RNAs help determine cashmere quality in goats.

Nanotechnology offers promising new treatments for PCOS by reducing inflammation and oxidative stress.

SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.

Researchers found a way to make rat hair follicle cells start turning into motor neuron-like cells, but couldn't fully turn them into working motor neurons.

Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

The cyst had unusual keratin spherules and resembled bone marrow.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

Oral Acitretin effectively resolved symptoms in a child with Netherton syndrome.

Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.

NIPP1 is important for healthy skin and could help treat skin inflammation.

A severe form of Netherton syndrome caused by a specific gene mutation led to neonatal deaths in a family.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.