research Immune-Mediated Diseases of the Central Nervous System
The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.
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research NOVEL CORONAVIRUS (SARS-COV-2): MOLECULAR BIOLOGY, PATHOGENESIS, PATHOBIOLOGY AND ADVANCES IN TREATMENT OF COVID-19 PATIENTS– AN UPDATE
COVID-19 is caused by a virus from bats, and efforts focus on prevention and treatment research.
research Optimizing Hyaluronic Acid: A Comprehensive Review of Rheological Insights for Clinical Practice
Understanding the properties of hyaluronic acid helps improve its use in facial aging treatments.
research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Potential role and therapeutic interests of myo-inositol in metabolic diseases
Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Epigenetic regulation in adult stem cells and cancers
Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
research Insertional mutation of the hairless locus on mouse Chromosome 14
A gene mutation in mice causes permanent hair loss and skin issues.
research Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5
A gene called Gk5 controls lipid production in the skin and affects hair growth.
research Chemistry, biological activities and toxic effects of alkaloidal constituents of genus Delphinium - A mini review
Delphinium plants have both medicinal benefits and toxic effects due to their alkaloids.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
research ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Phytochemical composition, antibacterial and antioxidant activities of the ethanolic root extract of the endemic Onosma, northern Iran.
The ethanolic root extract of Onosma dichroantha has strong antioxidant and antibacterial properties.
research Metabolomic analysis of SMP30/GNL knockout mice treated with fermented vegetable and fruit extract (OM-X®)
OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.
research Monocyclic Aromatic Compounds
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Exploring Phytotherapy For Alopecia: Efficacy, Mechanisms, And Future Directions
Herbal remedies might help with hair loss but need more research for safety and effectiveness.
research The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research VIII International Conference "Interdisciplinary aspects of diseases of the skin and mucous membranes" 11-12th March 2022
Higher IL-31 levels are linked to worse itching in chronic kidney disease patients.
research Effect of decellularisation methods on methacryloyl-substituted placental ECM hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research Skin and hair disorders
Accurate diagnosis and treatment of skin and hair disorders are crucial, with growing focus on hair loss treatments like topical minoxidil.
research Phytochemical studies on traditional herbal medicines based on the ethnopharmacological information obtained by field studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research AN OVERVIEW OF ANTI-INFLAMMATORY, ANTIOXIDANT, ANTI-CANCER, ANTI-HYPERLIPIDEMIC, NEUROPROTECTIVE AND MUSCLE RELAXANT EFFECTS OF NATURAL FLAVONOID, APIGENIN; A REVIEW
Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Alginate and its application to tissue engineering
Alginate is great for tissue engineering because it's safe, easy to use, and helps heal tissues.