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Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

NLCs with manual massage greatly improve clobetasol delivery to hair follicles.

Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

High doses of finasteride cause cell growth and tumors in mice.

Adiponectin boosts lipid production in skin cells, potentially helping treat skin conditions with low sebum.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Surface and internal treatments can help prevent hair lipid loss during washing.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Hair test results can be misleading due to contamination, so they shouldn't be used alone to determine drug use.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Three finasteride forms exist; "form X" doesn't.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

Lipid–polymer hybrid nanoparticles can improve genome editing delivery and outcomes.

New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Bilobetin may help reduce acne by decreasing sebum production.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Compound 15a was effective in inhibiting 5α-reductase.

Malassezia furfur lipids improve skin health at pH 6.

The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.