research Organization of microfibrils in keratin fibers studied by X-ray scattering
The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
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120-150 / 1000+ resultsresearch Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research Elucidating penetration pathways into the hair fiber using novel microscopic techniques.
The conclusion is that substances can penetrate hair fibers through multiple pathways, including both the cell membrane complex and the non-keratinous parts.
research Detection of Iodine by Scanning Electron Microscopy(SEM) and Energy Dispersive Spectroscopy(EDS) Following Contact with an Iodine Releasing Coating
The method successfully visualizes iodine in biological tissues.
research Application of second near infrared fluorescence imaging to trace CelTrac1000-labeled hair follicle epidermal neural crest stem cells in repairing rat facial nerve defects
NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research The failure behavior of the anchorage of hairs during slow extraction
Growing hairs are easier to pull out than resting hairs due to different anchorage strengths.
research Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Microneedles-A new paradigm in transdermal delivery of therapeutic agents
Microneedles offer a painless, effective way to deliver drugs through the skin.
research A Raman spectroscopy investigation of the resilience of hair cuticular scales under uniaxial stress
research Optical evaluation of internal damage to human hair based on second near‐infrared window polarization microscopy
A new method using near-infrared light can effectively detect and analyze internal hair damage.
research Microneedles in the clinic
Microneedles are being used and tested for various medical and cosmetic treatments.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
research MICRONEEDLE: AN OVERVIEW
Microneedles offer a painless way to deliver drugs effectively but need more research before they can be widely used.
research High spatial resolution study of human skin using synchrotron infrared microscopy: application to the penetration of external agents
External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
research Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing
The microneedles effectively kill MRSA and improve wound healing.
research Expression of nicastrin, NICD1, and Hes1 in NCSTN knockout mice: implications for hidradenitis suppurativa, Alzheimer’s, and liver cancer
research Optimized Microwell Array Device for Preparation of Hair Follicle Germ-like Aggregates
Pen-type microwells are best for forming hair follicle germ structures.
research Tactile and hair-hair friction behavior of hair fibers
Hair feels different when touched and rubs together in various ways.
research Pulling force deforms hair follicle root sheath nuclei and surrounding dermal collagen matrix differently at infundibulum, isthmus and suprabulbar regions
Hair follicles respond differently to pulling forces in various regions.
research Microneedle-Based Approaches for Skin Disease Treatment
Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns
Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.
research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
Potential compounds may inhibit hair loss by targeting a non-androgen pathway.
research Minoxidil Nanosuspension-Loaded Dissolved Microneedles for Hair Regrowth
New microneedle method improves hair regrowth treatment delivery.
research Mouse tail skin wholemount staining and intravital calcium imaging
The method helps study hair follicle stem cells and calcium signals in mouse skin.
research In-Situ Tensile Testing of Hair Fibers in An Environmental Scanning Electron Microscope (ESEM)
Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research Micro-mechanical approaches to characterize tip growth: Insights into Root Hair Elasto-Viscoplastic Properties
Root hair stiffness is mainly influenced by tip compression and turgor pressure.
research Investigating the origins of nanostructural variations in differential ethnic hair types using X‐ray scattering techniques
Different ethnic hair types have unique nanoscopic and molecular features despite having the same basic keratin structure.
research Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance
Darkened knuckles can be an early sign of insulin resistance.