research The chronic phase of Stevens-Johnson syndrome and toxic epidermal necrolysis: beyond skin and eyes
SJS and TEN can cause long-term organ damage and psychological issues beyond skin and eye problems.
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research Drug induced hair loss.
Naproxen is not the cause of hair loss in a child; it's due to a toxic event with expected hair regrowth.
research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features
A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.
research Metformin protects against gentamicin-induced hair cell death in vitro but not ototoxicity in vivo
Metformin protects hair cells in lab tests but not in live animals.
research Follicular penetration of nano-sized particulate FA-PLGA and the dye RhBITC in dorsal dog and rat skin, and porcine ear skin as an in vitro model for the human integument
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
research Toxic and Metabolic Disorders of the Nervous System
Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.
research Microneedles: Selected Applications for Pediatrics
Microneedles could revolutionize pediatric medicine by offering painless drug delivery, but more development is needed.
research The influence of sebaceous content on the performance of nanosystems designed for the treatment of follicular diseases
Excess sebum reduces the effectiveness of nanosystems for treating hair follicle conditions.
research Effects of Selenium and Other Micronutrient Intake on Human Health
Selenium is essential for health, but too little or too much can cause serious health problems.
research Possible Health Implications Associated with Cosmetics: A Review
Cosmetics can contain harmful chemicals that may cause serious health problems over time.
research Microneedles in the clinic
Microneedles are being used and tested for various medical and cosmetic treatments.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
research Dissolving microneedles: Applications and growing therapeutic potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Injectable Ag nanoclusters-based hydrogel for wound healing via eliminating bacterial infection and promoting tissue regeneration
The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
research Studies of the components of an oral contraceptive agent in albino rats. II. Progestogenic component and comparison of effects of the components and the combined agent
High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
research Dissolving microneedles: an advanced approach for transdermal drug delivery
Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.
research Aqueous Extract of Bacopa procumbens and the NAPEL Formulation Mitigate MPTP-Induced Neurotoxicity via Nrf2/HSF1/HIF-1α Signaling in a Parkinson’s Disease Model
Bacopa procumbens extract may help protect the brain in Parkinson's disease.
research Selenium Toxicity in Domestic Animals
Selenium can be toxic to animals, causing serious health issues, especially in horses.
research A Case of Inflammatory Nonscarring Alopecia Associated With the Tyrosine Kinase Inhibitor Nilotinib
A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.
research An accessible pharmacodynamic transcriptional biomarker for notch target engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research Finasteride Induced Clinical Ocular Toxicity
research Thermo‐Responsive Polymer‐Based Nanoparticles: From Chemical Design to Advanced Applications
Thermo-responsive polymers in nanoparticles enable targeted drug delivery and advanced therapies by releasing drugs at specific temperatures.
research K6/ODC transgenic mice as a sensitive model for carcinogen identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research A study of scarless wound healing through programmed inflammation, proliferation and maturation using a redox balancing nanogel
The nanogel helps wounds heal without scars.
research Dacomitinib-Induced Paronychia Associated With PRIDE Syndrome in a Patient With Non-Small Cell Lung Cancer
Dacomitinib can cause nail and skin issues, but these can be managed without stopping the drug.
research Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice*1
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
research Nanoemulgel: For Promising Topical and Systemic Delivery
Nanoemulgel is a better way to deliver drugs through the skin for various conditions.
research In situ formed fluorescent gold nanoclusters inhibit hair follicle regeneration in oxidative stress microenvironment via suppressing NFκB signal pathway
Tiny glowing gold particles can stop hair growth by blocking a specific cell signal.
research Nitroxide pharmaceutical development for age-related degeneration and disease
Nitroxide drugs can safely and effectively treat age-related diseases like macular degeneration and cardiovascular issues.