May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study focused on creating a chitosan-based minoxidil nanogel to enhance the topical treatment of alopecia by improving drug retention and targeting. The optimized nanogel, developed using the ionic gelation method and Box–Behnken design, had a particle size of 135.4 nm, a low polydispersity index, a high positive zeta potential, and an entrapment efficiency of 89.7%. It demonstrated skin-compatible pH, pseudoplastic rheological behavior, good spreadability, and physical stability. In vitro studies showed sustained drug release over 48 hours and better drug deposition compared to conventional solutions, indicating its potential as an effective treatment for alopecia.
October 2025 in “Journal of Nanobiotechnology” The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
Nanotechnology shows promise for better hair loss treatments but needs more research for safety and effectiveness.
January 2025 in “SSRN Electronic Journal” 
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hair follicles can be used to deliver drugs effectively, especially with nanoparticles, for treating skin conditions.
16 citations
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November 2023 in “Scientific Reports” The niosomes effectively target hair follicles for acne treatment.
3 citations
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January 2023 in “Materials horizons” The new biomaterial helps grow blood vessels and hair for skin repair.
22 citations
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October 2019 in “International Journal of Nanomedicine” The nanoparticles improved hair growth and enlarged hair bulbs.
March 2025 in “Advanced Science” Bioengineered hair germs using special hydrogels can help regenerate hair follicles and treat hair loss.
3 citations
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October 2024 in “World Journal of Advanced Research and Reviews” Silver nanoparticles are useful in medicine and technology for their antibacterial properties and potential in drug delivery and dentistry.
January 2021 in “Figshare” Tiny lipid particles carrying 17-α-estradiol gather in hair follicles, which may help target alopecia treatment.
January 2026 in “Preprints.org” Nanotechnology shows promise for treating hair loss but faces safety and approval challenges.
July 2024 in “Journal of Controlled Release” Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
1 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A new tool allows easier long-term imaging of live skin cells, helping study diseases like skin cancer.
10 citations
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July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
10 citations
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August 2024 in “ACS Omega” Nanocosmetics with natural extracts offer benefits but need more research on safety and environmental impact.
13 citations
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February 2019 in “Journal of Microencapsulation” The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.
August 2025 in “MedComm – Biomaterials and Applications” Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
35 citations
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February 2024 in “Science Advances” Magnetic fields help create complex 3D soft structures for biomedical use.
18 citations
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September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
3 citations
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November 2024 in “International Journal of Pharmaceutics” Larger positively charged gelatin nanoparticles are more effective for delivering treatments to hair follicles.
November 2024 in “Journal of Investigative Dermatology” Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
17 citations
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July 2018 in “International Journal of Cosmetic Science” Keratin-based particles safely improve hair strength, smoothness, and heat protection.
May 2026 in “Colloids and Surfaces B Biointerfaces” 
January 2024 in “Biomaterials Science” The method could grow hair in lab settings without using animals.
4 citations
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March 2023 in “Journal of controlled release” A special gel with medicine helps prevent melanoma from coming back after surgery.
1 citations
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August 2025 in “Frontiers in Pharmacology” Dissolving microneedles improve the delivery of traditional Chinese medicine by making it easier, safer, and more effective.
January 2020 in “Journal of the Brazilian Chemical Society” Tiny lipid particles loaded with a hormone gather in hair follicles, which may help treat hair loss.
12 citations
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September 2024 in “JID Innovations” Skin-on-a-chip devices better mimic human skin for research.