26 citations
,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
26 citations
,
July 2012 in “Epilepsy & Behavior” Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
23 citations
,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
22 citations
,
November 2005 in “BMC Cancer” Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
20 citations
,
September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
20 citations
,
February 1991 in “Archives of dermatology” High doses of tryptophan may cause eosinophilic fasciitis.
18 citations
,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
14 citations
,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
14 citations
,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
13 citations
,
August 2020 in “Frontiers in Immunology” Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
13 citations
,
October 2010 in “Pharmacogenomics” Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
13 citations
,
March 1998 in “Journal of Biomedical Materials Research” Island grafts can help study skin regeneration separately from other healing processes.
11 citations
,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
11 citations
,
November 2009 in “Brazilian Journal of Medical and Biological Research” Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.
10 citations
,
May 2018 in “Neuropharmacology” Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
9 citations
,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
9 citations
,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
8 citations
,
May 2024 in “PLoS Biology” Gap junctions help control feather pattern formation in chickens.
8 citations
,
August 2019 in “Dermatologic surgery” Nonsteroid treatments for alopecia areata show promise but need more high-quality research.
8 citations
,
October 2017 in “Dermatologic Surgery” Men need higher doses and tailored injection techniques for botulinum toxin treatments due to their unique facial features.
7 citations
,
March 2025 in “Archives of Dermatological Research” Trichoscopy helps better understand and manage alopecia areata, improving patient outcomes.
6 citations
,
March 2021 in “Cytotechnology” Mesenchymal stem cells show promise in treating COVID-19 by reducing inflammation and aiding recovery, but more research is needed.
5 citations
,
December 2024 in “Archivio Italiano di Urologia e Andrologia” Personalized treatment is crucial for effectively managing benign prostatic hyperplasia (BPH).
5 citations
,
January 2024 in “American Journal of Translational Research” Gut bacteria affect female reproductive health and may help diagnose and treat related diseases.
5 citations
,
January 2021 in “Journal of Saudi Chemical Society” Watercress oil may promote hair growth by activating specific receptors.
5 citations
,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
4 citations
,
June 2024 in “Journal of pharmacopuncture” Polygonum multiflorum shows promise for treating Alzheimer's and cognitive impairments.
3 citations
,
May 2024 in “Amino Acids” Disrupted cysteine metabolism may cause hair breakage in Alopecia Areata, suggesting potential treatments like N-acetylcysteine.
3 citations
,
May 2023 in “Frontiers in immunology” Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.