28 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” A patient had skin tissue death at the hair removal site after a hair transplant, which was treated with surgery.
12 citations
,
March 2017 in “Arteriosclerosis, thrombosis, and vascular biology” Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.
4 citations
,
October 2022 in “Aesthetic surgery journal” Injecting hyaluronidase into the artery is effective for treating skin death and hair loss caused by hyaluronic acid fillers.
1 citations
,
January 2014 in “Hair transplant forum international” Heavy smoking and other factors may lead to reduced blood flow and tissue death after hair transplant surgery.
79 citations
,
October 2003 in “PubMed” Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
61 citations
,
June 2010 in “Journal of the European Academy of Dermatology and Venereology” Anti-TNF-α therapy may increase the risk of developing alopecia areata, especially in those with a history of autoimmune disease.
53 citations
,
July 2009 in “Cancer Research” Blocking certain proteins can reduce skin inflammation caused by cancer treatment.
26 citations
,
March 2017 in “Aesthetic plastic surgery” Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.
26 citations
,
August 2014 in “Genetic Testing and Molecular Biomarkers” High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.
26 citations
,
March 2014 in “Rheumatology” Some drugs used to treat inflammation may cause hair loss.
26 citations
,
June 2005 in “Journal of The American Academy of Dermatology” Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.
24 citations
,
April 2013 in “PLOS ONE” TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
16 citations
,
July 2002 in “Australasian Journal of Dermatology” A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.
14 citations
,
May 1988 in “The Journal of Dermatologic Surgery and Oncology” The conclusion is that bilateral lateral scalp reduction has a high risk of severe complications, leading doctors to stop using it.
13 citations
,
March 1990 in “JAMA” Topical eye β-blockers might cause hair loss, which usually gets better after stopping the medication.
11 citations
,
September 2005 in “International Wound Journal” A woman developed severe skin damage after using a blood thinner called low-molecular-weight heparin.
8 citations
,
December 2023 in “International Journal of Molecular Sciences” Lower TNF-α levels in PRP may predict better treatment outcomes for bladder conditions.
7 citations
,
January 2017 in “Dermatology Online Journal” TNF-inhibitor induced alopecia can be treated effectively with different therapies.
6 citations
,
May 2023 in “Dermatology Research and Practice” IL-15 and TNF-α levels are higher in alopecia areata patients, especially in alopecia totalis.
6 citations
,
July 2015 in “Dermatology practical & conceptual” Feily's method prevents scalp necrosis in dense hair transplants by allowing time for blood flow to return before grafting.
5 citations
,
October 2018 in “Journal of Cosmetic Dermatology” Oral pulse steroids reduce TNF-α levels, improving alopecia areata.
5 citations
,
September 2016 in “Dermatologic Therapy” Feily's method, which delays grafting for 24 hours to improve blood flow, successfully prevented scalp necrosis in three hair transplant patients.
3 citations
,
June 2025 in “Archives of Dermatological Research” Stopping TNFα inhibitors can help children regrow hair lost due to the medication.
3 citations
,
August 2020 in “Journal of Cosmetic Dermatology” Topical nitroglycerin spray effectively prevents scalp necrosis in hair transplant patients.
2 citations
,
April 2023 in “Journal of Psoriasis and Psoriatic Arthritis” Early diagnosis and treatment are crucial to prevent permanent hair loss from TNFα inhibitors in scalp psoriasis.
2 citations
,
March 2023 in “Frontiers in medicine” A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.
2 citations
,
February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
2 citations
,
January 2014 in “Journal of clinical and investigative dermatology” Some drugs used to treat immune conditions may cause different types of hair loss.
1 citations
,
September 2023 in “Rheumatology advances in practice” A woman's rare scalp condition worsened after using a specific arthritis medication, suggesting such medications can sometimes trigger or aggravate psoriasis.
1 citations
,
April 2012 in “Informa Healthcare eBooks” Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.