49 citations
,
May 2020 in “The Scientific World JOURNAL” Mesotherapy is a skin injection therapy used for pain and local conditions, with scientific support but needing more clinical trials.
4 citations
,
May 2019 in “Journal of Cosmetic Dermatology” Using a smaller syringe causes less pain when giving an injection.
February 2025 in “International Journal of Dermatology” Pressure from injectable treatments can cause hair loss by compressing blood vessels.
17 citations
,
January 2023 in “Nanoscale Advances” The microneedle arrays effectively promote wound healing and have potential for clinical use.
13 citations
,
November 2022 in “Biomaterials Science” The microneedle patch effectively promotes hair regrowth by delivering miR-218.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Hyaluronic acid microneedles with herbal extracts may effectively promote hair growth for treating hair loss.
13 citations
,
April 2001 in “Journal of The American Academy of Dermatology” Using a vibrating device during injections can help reduce pain.
11 citations
,
July 2023 in “Applied Nanoscience” July 2025 in “Journal of Investigative Dermatology” AI-09 is safe, effective, and reduces wrinkles for up to 6 months.
June 2026 in “Journal of Pharmaceutical Innovation” May 2016 in “Hair transplant forum international” July 2018 in “Dermatologic Surgery” The review didn't provide clear conclusions on injectable treatments for hair loss.
January 2021 in “Advanced Biomedical Engineering” Needle shape affects the force needed for hair implants, with certain shapes reducing the effort required.
5 citations
,
January 2023 in “Journal of Cosmetic Dermatology” Intradermal microbotox injections work better and last longer for reducing large facial pores than topical application.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” Micro needling is a skin treatment that helps with various skin conditions including stretch marks, by boosting collagen production, but it may cause redness and irritation.
June 2026 in “ACS Applied Nano Materials” New microneedles may improve vitiligo treatment.
12 citations
,
November 2022 in “Cosmetics” 3D printed microneedles are likely to become more common in cosmetics for better skin delivery.
January 2023 in “Skin appendage disorders” Scalp microinfusion is a new method for treating hair loss that shows promise but needs more research for standardization.
3 citations
,
November 2022 in “Facial plastic surgery & aesthetic medicine” Using ultrasound to guide temple filler injections improves safety and accuracy.
August 2023 in “Chinese Journal of Dermatology” Microneedling is a safe and effective low-cost treatment for hair loss that works better and faster than traditional methods.
30 citations
,
January 2014 in “Journal of Controlled Release” This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
38 citations
,
March 2015 in “Journal of controlled release” IMSG nanoparticles improve vaccine delivery and immune response through hair follicles.
95 citations
,
July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
January 2026 in “Drug Delivery and Translational Research” Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
8 citations
,
November 2024 in “Journal of Cosmetic Dermatology” Injections are effective and safe for rejuvenating neck, chest, and hands.
19 citations
,
July 2019 in “Biomedical Microdevices” Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.
15 citations
,
May 2016 in “Die Pharmazie” Nanostructured lipid carriers deliver lidocaine to the skin better than nanoethosomes.
11 citations
,
June 1999 in “Seminars in Cutaneous Medicine and Surgery” The best hair transplant method depends on the desired look; faster techniques may not give better results or save money.
The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.
May 2024 in “Journal of biomaterials science. Polymer ed.” The three-layer microneedle system effectively delivers minoxidil into the skin, showing potential as a safe and efficient treatment for hair loss.