68 citations
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September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” A new Wnt surrogate specifically targets the Frizzled7 receptor, promoting organoid formation and hair growth.
6 citations
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July 2016 in “Doklady Biochemistry and Biophysics” GD-23 reduces anxiety by relying on neurosteroid production.
May 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.
36 citations
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May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
14 citations
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April 2009 in “Acta Medica Scandinavica” Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.
April 2024 in “AAPS PharmSciTech” New microneedle method improves hair regrowth treatment delivery.
November 2024 in “Skin Appendage Disorders” Start low-dose minoxidil gradually, especially for women, to reduce side effects.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
May 2024 in “Regenerative Therapy” Dendrobium officinale polysaccharide helps hair growth by activating the WNT signaling pathway.
25 citations
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June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
1 citations
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January 2005 in “Research Portal (King's College London)” Finasteride and DEHP exposure during development can change reproductive markers in rats.
October 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
February 2026 in “International Journal of Nanomedicine” Engineered exosomes with EGF and FGF improved hair growth in mice with hair loss.
28 citations
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September 2019 in “International Journal of Nanomedicine” Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
February 2022 in “Authorea (Authorea)” PAON shows skin patterns due to genetic mosaicism.
11 citations
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October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
October 2022 in “The Korean Journal of Physiology and Pharmacology” Targeting the PGD2-DP2 pathway may help treat hair loss.
April 2023 in “Journal of Investigative Dermatology” A new treatment for hair loss shows promise with fewer side effects.
October 2025 in “Journal of the Endocrine Society” The patient was satisfied with hormone therapy, and her epilepsy remained stable.
46 citations
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October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
"Coco de mono" seeds cause temporary hair loss due to selenocystathionine.
16 citations
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August 2014 in “International Journal of Women's Health” The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.
26 citations
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June 2020 in “Polymers” Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
November 2001 in “Oncology Times” The committee decided not to approve the drug due to low effectiveness and high risks.
2 citations
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January 2022 in “International Journal of Medical Sciences” Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.
December 2015 in “Endocrinology and Metabolic Syndrome”
December 1998 in “Acta Crystallographica Section C-crystal Structure Communications” A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.