research Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging
New methods have helped find cells that create other cells in the body.
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research Characterization of Human Dermal Papilla Cells in Alginate Spheres
Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair‐Follicle‐Derived Stem Cells to Differentiate into Neurons and Glia
Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
research ROBO4 deletion ameliorates PAF-mediated skin inflammation via regulating the mRNA translation efficiency of LPCAT1/LPCAT2 and the expression of PAF receptor
Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
research Skin eruptions specific to pregnancy: an overview
Pregnancy can cause unique skin issues, some of which may risk the mother and baby's health and need careful treatment.
research Managing the hair and skin of African American pediatric patients
The document emphasizes the need for primary care providers to understand and care for African American children's hair and skin to boost their self-esteem.
research Therapeutic potential of Sertoli cells in vivo: alleviation of acute inflammation and improvement of sperm quality
Sertoli cell transplants can reduce inflammation and improve sperm quality.
research Pregnancy in postpartum estrus induces inflammatory milk production and catagen specific pup skin inflammation in interleukin-10 deficient mice
Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
research Serenoa repens and N‐acetyl glucosamine/milk proteins complex differentially affect the paracrine communication between endothelial and follicle dermal papilla cells
Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
research Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss
Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
research Narrative Review of Skin and Pregnancy: Dermatologic Manifestations and Medication Management During Pregnancy
Pregnancy can cause skin changes and issues that need careful management.
research Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance
Niacinamide improves aging skin and is safe for use in cosmetics.
research Global Burden of Skin Disease as Reflected inCochrane Database of Systematic Reviews
The representation of skin conditions in medical reviews partly matches their real-world impact.
research Stress and the skin: Significance of emotional factors in dermatology
Stress affects skin health and emotional well-being should be considered in skin disease treatment.
research A systematic review of randomized controlled trials assessing phytochemicals and natural ingredients for skin and hair care
Natural ingredients can improve skin and hair, but more research is needed.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research Industry updates from the field of stem cell research and regenerative medicine in June 2019
In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.
research The eye and the skin in endocrine metabolic diseases
Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
research Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles
Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
research IL-17-producing γδ T cells enhance bone regeneration
IL-17-producing γδ T cells help improve bone healing.
research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
research Neuroprotective and immunomodulatory effects of human hair follicle stem cells on streptozotocin-induced memory impairment in rats: insights into inflammation and neurotrophic mechanisms
Human hair follicle stem cells improved memory and brain health in rats.
research Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats
The study identified key genes and pathways that influence goat wool quality and growth.
research Ephrin-A3 not only increases the density of hair follicles but also accelerates anagen development in neonatal mice
Ephrin-A3 helps increase and speed up hair growth in baby mice.
research Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin
A new imaging method helps see and study touch nerve endings in mouse skin.
research Nutraceuticals known to promote hair growth do not interfere with the inhibitory action of tamoxifen in MCF7, T47D and BT483 breast cancer cell lines
Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.