387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
13 citations
,
February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
16 citations
,
February 2022 in “Science Advances” Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
153 citations
,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
5 citations
,
December 2017 in “Tissue and cell/Tissue & cell” Researchers found stem cells in dog hair follicles using specific markers.
October 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Researchers developed a method to label and study human hair follicle stem cells using a fluorescent protein.
28 citations
,
January 1997 in “Elsevier eBooks” Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.
151 citations
,
February 2006 in “Stem Cells and Development” Hair follicles can be a good source of stem cells like those from bone marrow.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
26 citations
,
January 2014 in “Cell Structure and Function” Human sweat glands contain stem cells capable of self-renewal and forming different cell types.
1 citations
,
November 2025 in “Stem Cell Research & Therapy” Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
1 citations
,
April 2024 in “Cells” Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.
333 citations
,
February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
September 2008 in “Acta Ophthalmologica” Hair follicle stem cells can become corneal-like cells with the right environment.
6 citations
,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
2 citations
,
August 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin stem cells help create protective immune cells during wound healing.
128 citations
,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
25 citations
,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
12 citations
,
November 2015 in “Cell Death & Differentiation” Inflammation helps stem cells repair tissue by directing their behavior.
1 citations
,
July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
2 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Neural stem cells use local feedback to maintain balance in the adult brain.
July 2017 in “Cancer Research” Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.
5 citations
,
January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
3 citations
,
August 2012 in “Nature Cell Biology” Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
52 citations
,
October 2005 in “Journal of Investigative Dermatology” Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
January 2017 in “Journal of clinical & experimental dermatology research” Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.