165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
13 citations
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December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
10 citations
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January 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
38 citations
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July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
8 citations
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June 2024 in “APOPTOSIS” Caspases affect many cell functions and could help treat various diseases.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
84 citations
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December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
72 citations
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April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
59 citations
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April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
50 citations
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February 2007 in “Expert Opinion on Biological Therapy” Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
48 citations
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July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
45 citations
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April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
38 citations
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June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
33 citations
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September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
23 citations
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January 2017 in “Current Rheumatology Reports” Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.
22 citations
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November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
18 citations
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August 2021 in “PLoS ONE” Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
17 citations
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December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
12 citations
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December 2023 in “Journal of Applied Pharmaceutical Sciences and Research” Caffeine boosts alertness, helps breathing, acts as a diuretic, and may aid cancer treatment.
4 citations
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October 2025 in “International Journal of Medical Sciences” Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
4 citations
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June 2021 in “Basic and Clinical Neuroscience Journal” Rat hair follicle stem cells can improve nerve repair and muscle function after injury.
3 citations
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December 2020 in “Scientific reports” Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
2 citations
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November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
1 citations
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January 2018 in “Methods in molecular biology” The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
1 citations
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January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.
December 2025 in “EMBO Reports” Cells communicate with neighbors to coordinate their development.
November 2025 in “Nature Communications” Hair growth may involve a pulling force from the outer root sheath.