research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
Corneal cells can transform into skin and hair cells through specific signals.
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540-570 / 1000+ resultsresearch Regenerative Medicine-Based Treatment for Vitiligo: An Overview
Regenerative treatments for vitiligo show promise but need more research for long-term safety and effectiveness.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research Exosome-based Therapies for Androgenetic Alopecia: Mechanisms, MicroRNAs, and Clinical Prospects
Exosome therapy could be a promising new way to treat hair loss.
research Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs
TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
research Clinical and preclinical approach in AGA treatment: a review of current and new therapies in the regenerative field
New regenerative therapies show promise for treating hair loss.
research A Hairy Cituation – PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research SOX9 in organogenesis: shared and unique transcriptional functions
SOX9 is essential for the development of various organs and hair follicles.
research Functional regeneration strategies of hair follicles: advances and challenges
Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
research iPSC-based approach for human hair follicle regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
research NG2 Proteoglycan Expression in Mouse Skin: Altered Postnatal Skin Development in the NG2 Null Mouse
NG2 is crucial for normal skin and hair development in mice.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Modern strategies for the prevention and treatment of post-burn scars (a systematic review)
Combining surgical and nonsurgical methods is key to reducing post-burn scars.
research A skin organoid-based infection platform identifies an inhibitor specific for HFMD
NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
research Organoids in skin wound healing
Skin organoids help improve wound healing and tissue repair.
research Intrinsic and Extrinsic Factors Associated with Hair Graying (Canities) and Therapeutic Potential of Plant Extracts and Phytochemicals
Plant extracts may help prevent or reverse hair graying.
research Investigation of Glypican-4 and -6 by Infrared Spectral Imaging during the Hair Growth Cycle
Infrared spectral imaging can effectively study protein distribution in hair follicles during hair growth.
research ASH2L mediates epidermal differentiation and hair follicle morphogenesis via H3K4me3 modification
ASH2L is essential for skin and hair development.
research Proceedings of the Ninth World Congress for Hair Research (2015)
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research 3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects
3D spheroid culture makes stem cells better at reducing inflammation.
research Engineered extracellular vesicles for tissue repair and regeneration
Engineered extracellular vesicles can improve tissue repair and regeneration.
research Mitochondria-Targeted Biophysical Priming of Autologous Biologics for Skin Regeneration and Wound Repair
Targeting mitochondria can improve skin healing and rejuvenation.
research 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration
4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
research A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus
Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
research Human Hair Graying Revisited: Principles, Misconceptions, and Key Research Frontiers
Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
research Hairy tale of signaling in hair follicle development and cycling
Hair growth and development are controlled by specific signaling pathways.