research Androgen receptor–mediated inhibition of cutaneous wound healing
Lowering testosterone speeds up wound healing in male mice.
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research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
research Regulation of the innate immune response in rheumatoid arthritis
More research is needed to understand and manage rheumatoid arthritis better.
research Neurosteroids on the Epilepsy Chessboard—Keeping Seizures in Check
Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
research Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
research Causal Link of Distinct Mental Disorders with Androgenetic Alopecia and Alopecia Areata: A Bidirectional Two-Sample Mendelian Randomization Study
Major depression disorder increases the risk of alopecia areata, and vice versa.
research Stress and the Hair Follicle
Stress can cause hair loss and skin issues by affecting hair growth cycles.
research The effect of finasteride on anxiety in rats
Finasteride may increase anxiety in bright spaces.
research Finasteride withdrawal induces anxiety-like behavior and novelty avoidance in adult male rats.
Finasteride withdrawal causes anxiety-like behavior in male rats.
research Expression of Hypothalamic–Pituitary–Thyroid Axis RelatedGenes in the Human Skin
Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
research 6 Current concepts of polycystic ovary syndrome
PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
research Skin ‑ a vast organ with immunological function (Review)
The skin is a large organ that plays a role in the immune system.
research Utility of GLI1 RNA Chromogenic in Situ Hybridization in Distinguishing Basal Cell Carcinoma From Histopathologic Mimics
GLI1 RNA CISH effectively identifies basal cell carcinoma but is less specific for benign follicular tumors.
research Mechanism of action and promising clinical application of melatonin from a dermatological perspective
Melatonin may help treat skin conditions.
research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP3‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles
Caffeine may help reduce stress-induced hair loss.
research Association Between Hair Diseases and COVID-19 Pandemic-Related Stress: A Cross-Sectional Study Analysis
The study suggests pandemic stress might worsen or trigger hair loss problems.
research How actual is the treatment with antiandrogen alone in patients with polycystic ovary syndrome?
Antiandrogens help manage PCOS symptoms but need careful monitoring.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Psychological Aspects of Hair Disorders: Consideration for Dermatologists, Cosmetologists, Aesthetic, and Plastic Surgeons
Hair loss can cause stress and mental health issues, so treatments should address both the physical and psychological aspects, involving a team of dermatologists, psychologists, and hair specialists.
research Universal Dermatology: Bridging Gaps in Skin Health
Inclusive dermatology aims to provide personalized skin care for all by addressing diverse needs and disparities.
research Obesity in Adults: Position Statement of Polish Association for the Study on Obesity, Polish Association of Endocrinology, Polish Association of Cardiodiabetology, Polish Psychiatric Association, Section of Metabolic and Bariatric Surgery of the Association of Polish Surgeons, and the College of Family Physicians in Poland
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Unraveling Evolutionary Insights into AVT Peptide Conservation and Antimicrobial Motif Prediction Across Taxa
AVT is highly conserved and may have antimicrobial properties.
research Pre-pregnancy BMI as a Risk Factor: Associations with Maternal Hair Cortisol and Child Psychopathology at Age Two
Higher pre-pregnancy BMI is linked to more stress in mothers and more behavioral problems in two-year-old children.
research How to Choose the Optimal Starting Dose of Clomiphene Citrate (50 or 100 mg per Day) for a First Cycle of Ovulation Induction in Anovulatory PCOS Women?
Choosing the right starting dose of Clomiphene Citrate for ovulation induction in PCOS women is challenging; higher BMI and hormone levels may indicate resistance to the standard dose.
research Molecular expression associated with vibrissa follicle development and differentiation
Id proteins, especially Id2 and Id3, are crucial for hair follicle development and stem cell regulation.
research Weak correlations between serum and cerebrospinal fluid levels of estradiol, progesterone and testosterone in males
Blood hormone levels don't accurately show brain hormone levels in males.
research Dermatologic manifestations of thyroid disease: a literature review
Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.
research Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner
research Exploring the Potential Links between Telogen Effluvium, Alopecia Areata, Pressure-Induced Alopecia, and General Anesthesia: A Narrative Review
General anesthesia might be linked to certain types of hair loss, but more research is needed.