66 citations
,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
61 citations
,
January 2019 in “American Journal of Clinical Dermatology” The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
54 citations
,
August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
46 citations
,
April 2008 in “Archives of Dermatological Research” Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
41 citations
,
March 2010 in “Psychology Research and Behavior Management” Using psychological treatments can help manage skin conditions along with regular medical care.
28 citations
,
May 1994 in “The Journal of Urology” Topical minoxidil not effective for erectile dysfunction treatment.
22 citations
,
November 2014 in “Psychiatric Clinics of North America” Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
9 citations
,
January 2023 in “Cellular and Molecular Life Sciences” Botulinum toxin A can help improve thin endometrium and embryo implantation.
6 citations
,
September 2010 in “Current Urology Reports” New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.
4 citations
,
February 2020 in “Cell & tissue research/Cell and tissue research” Hair follicle stem cells might help treat traumatic brain injury.
2 citations
,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
1 citations
,
May 2008 in “Toxicon” The lowest effective dose of Botox for detrusor sphincter dyssynergia is between 75-100 units.
Elderly skin care needs personalized treatment, early intervention, and integrated psychiatric care.
Understanding hair follicle signaling can improve hair disorder treatments.
December 2025 in “Cosmoderma” Systemic corticosteroids help manage vitiligo by slowing progression and aiding repigmentation.
August 2021 in “Benha Journal of Applied Sciences” Stress can trigger and worsen vitiligo.
November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
7 citations
,
September 2020 in “Frontiers in Cell and Developmental Biology” IL-36α helps grow new hair follicles and speeds up wound healing.
4 citations
,
February 2025 in “GeroScience” Increasing neuropeptide Y in the brain can slow aging signs in mice.
2 citations
,
January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
September 2015 in “Actas Dermo-Sifiliográficas” People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.
13 citations
,
October 2015 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
281 citations
,
January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
234 citations
,
April 2000 in “Gene” Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.