69 citations
,
October 2013 in “Tissue Engineering Part A” Keratin hydrogel improves nerve regeneration and motor recovery.
419 citations
,
March 2005 in “Proceedings of the National Academy of Sciences” Hair-follicle stem cells can become neurons.
1 citations
,
January 2003 Merkel cells likely attract sensory nerve fibers.
3 citations
,
May 2008 in “Journal of Visualized Experiments” Mouse Epidermal Neural Crest Stem Cells can become various cell types.
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
63 citations
,
February 2010 in “Journal of Neurophysiology” Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
7 citations
,
September 2013 in “Tissue engineering. Part A” Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
1 citations
,
January 2001 in “PubMed” Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
3 citations
,
January 2016 NuMA-microtubule interactions are crucial for proper skin structure and hair growth.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
63 citations
,
December 2010 in “Journal of Endocrinology” Reduced neurosteroids and growth issues can harm fetal brain development, especially in males.
19 citations
,
February 2013 in “Journal of Investigative Dermatology” Touch domes in human skin are complex sensory structures not directly linked to hair.
34 citations
,
January 1998 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.
NuMA-microtubule interactions are vital for proper skin structure formation and function.
37 citations
,
January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
January 2014 in “International Journal of Dermatology and Venereology” A man with hair loss and a scalp lump was diagnosed with a diffuse neurofibroma but chose not to have surgery.
September 2004 in “Experimental Dermatology” The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
July 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” A new wearable device stops hair loss and boosts hair growth safely.
5 citations
,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
December 2021 in “Morphologia” Neural crest cells could be used in regenerative medicine due to their ability to become different cell types.
December 2022 in “Stem Cells and Development” Exosomes from stem cells help improve nerve repair in rats.
January 2025 in “Online Publication Service of Würzburg University (Würzburg University)” A protocol was developed to create 3D skin models from adult diseased cells to study Small Fiber Neuropathy.
November 2023 in “Research Square (Research Square)” NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
1 citations
,
May 2008 in “Journal of Experimental Biology” Different species have unique sensory adaptations to perceive their environments.
7 citations
,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
13 citations
,
August 2023 in “Developmental Cell” Mechanosensory neurons adapt to different skin types after birth.
January 2024 in “Wiadomości Lekarskie” AI and robotics are improving treatment and monitoring of neurodegenerative disorders like Parkinson's.
June 2026 in “Scientific Reports” The study investigates the gene expression profiles of nestin-expressing hair follicle-derived cells (NHFCs) and compares them to other stem/progenitor cell systems. NHFCs show significantly higher levels of neurotrophic factors like Bdnf, Ngf, and Vegf, suggesting strong neuroprotective properties. They also exhibit a unique expression pattern of neural differentiation markers, with lower Nes and higher Tubb3 levels, indicating a tendency towards neuronal maturation. The presence of both neuronal and glial markers highlights NHFCs' distinct differentiation potential, positioning them as promising candidates for neuroregenerative therapies and regenerative medicine.
April 2009 in “The FASEB Journal” Keratin biomaterials from human hair help nerve regeneration by activating Schwann cells.