research Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats
Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
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720-750 / 1000+ results research Hair steroid before and after COVID-19 in preschoolers: the moderation of family characteristics
Family dynamics affect preschoolers' stress levels, especially DHEA.
research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research A Preliminary Assessment of Steroid Reproductive Hormones in Archaeological Human Hair Utilizing a Modified Enzyme-Linked Immunosorbent Assay (ELISA) Technique
Steroid hormones can be preserved in ancient hair, revealing insights into past health and fertility.
research Finasteride/testosterone
research 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level
Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.
research The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin levels: A secondary study from the WHICH randomized clinical trial
Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.
research Ligand Based 3D-QSAR Study on a Series of Steroidal Human 5α-Reductase Inhibitors
research Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In vitro Studies on Human Skin
Hair follicles and glands significantly increase steroid absorption in skin.
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
research Flurandrenolide
research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams
research Structural basis for the catalysis and inhibition of human steroid 5α‐reductase 2
The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors
research Cerebronal® food supplement improve status of markers ofdementia and regeneration
Cerebronal® may help improve certain brain health markers.
research HAIR COAT AND STEROIDAL IMPLANT EFFECTS ON STEERS GRA ZING NDOPHYTE-INFECTED TALL FESCUE DURING THE SUMMER
Steers with winter hair coats and reduced sweating struggled with heat, leading to less grazing and poor performance.
research The efficacy of an adjuvant norethisterone (jenapharm) therapy in endometrial cancer
Norethisterone (jenapharm) therapy is effective for endometrial cancer.
research Human Osteoblast-Like Cells Express Predominantly Steroid 5α-Reductase Type 1
Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.
research Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men
DHEA is the main sex steroid in cerebrospinal fluid, and testosterone in the fluid comes from the blood.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research Epitestosterone
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles
The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives
research Post-steroid panniculitis: a lost and forgotten entity?
Post-steroid panniculitis is now rare because doctors taper steroids more carefully.
research The Role of miR-214-3p in Hair Follicle Neural Crest Stem Cell-derived Exosomes in the Repair of Peripheral Nerve Injury
miR-214-3p helps nerve repair and recovery.
research Antibacterials/corticosteroids/minoxidil
research Finasteride
research The potential of nestin-expressing hair follicle stem cells in regenerative medicine
Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.