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April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
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January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
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July 2001 in “Journal of The American Academy of Dermatology” Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
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August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
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March 2013 in “Circulation Research” K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
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September 1987 in “JAMA” IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
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June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
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September 2008 in “Journal of Burn Care & Research” Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
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December 2020 in “Mayo Clinic Proceedings” The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
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February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
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June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
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March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
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August 1992 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect hormone levels in normal men.
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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
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April 2003 in “Journal of dermatology” Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.
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June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
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November 2021 in “BMJ Open” People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
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July 2011 in “Animal science journal” Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
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March 2014 in “ISRN Biomaterials” Keratin hydrogel from human hair helps rats recover better from spinal cord injuries.
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
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June 2020 in “Dermatology and therapy” Narrowband-UVB phototherapy successfully treated a rare case of Graham Little-Piccardi-Lassueur syndrome.
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April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Astrotactin2 affects hair follicle orientation and skin cell polarity.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.