September 2022 in “KnE medicine” Argan oil in hair tonic increases hair growth and weight in mice, with the best results at 3% concentration.
December 2023 in “Asian journal of beauty & cosmetology” 3 citations
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December 2015 in “Asian journal of dermatology” Natural plant extracts with sweet flag can significantly reduce hair loss and increase hair density and thickness in people with alopecia.
15 citations
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October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
3 citations
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January 2025 in “International Journal of Molecular Sciences” EGCG shows strong electron transfer interactions when bonded to DPPG lipids.
1 citations
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July 2012 in “EFSA Journal” The combination of certain vitamins and pumpkin seed oil has not been proven to maintain normal hair.
82 citations
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May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
November 2025 in “Journal of Investigative Dermatology” The study investigates the effects of N,N-Dimethylglycine sodium salt (DMG-Na) on human skin cells, revealing its potential as a multifaceted skin treatment. DMG-Na promotes cell proliferation, migration, and VEGF release in HaCaT keratinocytes, while exhibiting anti-inflammatory and antioxidant properties in models of skin diseases. It increases intracellular calcium and nitric oxide production in HDMECs, enhancing skin blood flow. In dermal papilla cells, DMG-Na reverses senescence-associated changes, indicating anti-aging benefits. A pilot study with a 1% DMG-Na gel confirmed its vasodilatory effects. These findings suggest DMG-Na could treat various skin conditions, including hair loss, with further clinical studies underway to assess its broader therapeutic potential.
November 2022 in “Journal of Investigative Dermatology” A new molecule was found to be a safe and effective skin lightener and anti-aging product.
15 citations
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October 2006 in “Journal of the American Academy of Dermatology” Liquid nitrogen spray caused a temporary, harmless swelling under the skin in an elderly woman.