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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

TRPV4 channel affects skin health and could be a target for treating skin disorders.

DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

The study developed a 3D model that closely imitates remaining ovarian cancer after treatment and identified a potential drug targeting resistant cancer cells.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.

TRPV3 is important for skin health and could be a target for treating skin diseases.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Bubble microneedles effectively deliver drugs through skin and mouth, improving hair growth and lowering glucose.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Microneedling with topical dutasteride improves hair growth in men with hair loss and is safe to use.

PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.

Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.

FOL-026 peptide may help hair growth and cardiovascular health by improving blood flow and cell functions.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Chronic ethanol increases certain brain receptor levels, influenced by steroids and protein changes.

Dopamine affects coat color changes in agouti mice.

Special astroglia cells improved stroke recovery in rats, a hair growth drug reduced cancer spread, and tiny magnesium structures were more easily shaped.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.