research Matrix remodelling and MMP expression/activation are associated with hidradenitis suppurativa skin inflammation
Matrix changes and increased MMPs contribute to skin inflammation in hidradenitis suppurativa.
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300-330 / 1000+ resultsresearch New Modalities in the Treatment of Refractory Alopecia Areata
New treatments focusing on immune pathways show promise for stubborn hair loss.
research Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients
Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.
research Kinetic topographical heterogeneity in follicular thyroid neoplasms and growth patterns
Different growth patterns in thyroid tumors are influenced by where cell growth and death occur.
research 1327 Effect of ginsenoside Rd on dermal epidermal junction in fibroblast
Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research 1323 The effects of 3-OH of kaempferol on interfollicular epidermal stem cell fate
Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.
research 1326 Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling
research Efficacy and Safety of Topical Calcipotriol 0.005% Versus Topical Clobetasol 0.05% in the Management of Alopecia Areata: An Intrasubject Pilot Study
Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.
research Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions: A preliminary study
White hair follicles in vitiligo have fewer and less functional melanocytes.
research A New Combination Therapy for Scalp Alopecia Areata: A Study of High Negative Pressure Microdermabrasion + Intralesional Steroids
Combining microdermabrasion with steroid injections improves hair regrowth in scalp alopecia areata.
research Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells
HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
research 1321 Endocannabinoid-like molecule oleoylethanolamide promotes sebaceous lipid synthesis
Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.
research Systemic Corticosteroids in Vitiligo
Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.
research 1320 Orchestrated cytotoxic and skin migratory ability lacking self-tolerance: circulating γδT-cells may promote alopecia areata
The role of γδT-cells in causing alopecia areata remains unclear.
research 1316 Aqueous extract of Mentha suaveolens induces Nrf-2 activation and expression of antioxidant and detoxifying enzymes in human keratinocyte HaCaT
Mint water extract boosts protective enzymes in skin cells.
research 1319 Claudin-1 and -3 maintain proper hair follicle structure and regulate telogen effluvium
Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research Randomized comparison of topical betamethasone valerate foam, intralesional triamcinolone acetonide and tacrolimus ointment in management of localized alopecia areata
Intralesional triamcinolone acetonide is the most effective treatment for localized alopecia areata.
research Trichodysplasia of immunosuppression treated with oral valganciclovir
Oral valganciclovir improved a patient's skin condition caused by immunosuppression.
research The effects of narrowbands of visible light upon some skin disorders: a review
Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
research Anticytokine therapy, particularly anti-IFN-γ, in Th1-mediated autoimmune diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research Segmental Vitiligo
Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.
research Retrospective Analysis of Systemic Corticosteroids for Alopecia Areata in Pediatric Patients
Systemic steroids temporarily improve severe alopecia areata in children but often lead to relapse.
research Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications
Distinct miRNA signatures could help diagnose and treat severe Alopecia Areata.
research Early skin seeding regulatory T cells modulate PPARγ-dependent skin pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research Retrospective Analysis of Pediatric Alopecia Areata Treated with Methotrexate
Methotrexate may effectively and safely treat hair loss in children, with notable improvement after 12-15 months.
research Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Secondary Cicatricial and other Permanent Alopecias
The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.