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Did you mean Nonmelanoma Skin Cancer?

GlossaryNonmelanoma Skin Cancer

refers to skin cancers excluding melanoma, like basal and squamous cell carcinomas

Nonmelanoma Skin Cancer (NMSC) refers to a group of skin cancers that are not melanoma, the most common types being basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). These cancers typically develop in the outer layer of the skin (epidermis) and are usually caused by prolonged exposure to ultraviolet (UV) radiation from the sun or tanning beds. While NMSC is generally less aggressive than melanoma and has a higher survival rate, early detection and treatment are crucial to prevent potential disfigurement and complications.

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research Characteristics of non‐melanoma skin cancers of the cutaneous perioral and vermilion lip treated by Mohs micrographic surgery

8 citations , October 2018 in “Journal of the European Academy of Dermatology and Venereology”

Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.

research 014 Non-melanoma skin cancer in skin of color: Cases of mistaken identity

September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

Non-melanoma skin cancer in darker-skinned people can be misdiagnosed, so doctors need to be more aware to diagnose it correctly and early.

research Targeting nonmelanoma skin cancer using selective photothermolysis with 595 nm pulsed dye laser: Outcomes of 1080 cases

May 2017 in “Journal of The American Academy of Dermatology”

595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.

research Nonmelanoma skin cancer treated with electronic brachytherapy: Results at 1 year

78 citations , January 2013 in “Brachytherapy”

HDR electronic brachytherapy effectively treats nonmelanoma skin cancer with good cosmetic results and minimal side effects.

Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

1 citations , January 2023 in “International Journal of Molecular Sciences”

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

research Effect of Liquid Blood Concentrates on Cell Proliferation and Cell Cycle- and Apoptosis-Related Gene Expressions in Nonmelanoma Skin Cancer Cells: A Comparative In Vitro Study

December 2024 in “International Journal of Molecular Sciences”

Platelet-rich fibrin may help reduce nonmelanoma skin cancer cell growth.

research 874 Elevated expression of osteopontin splice variants in nonmelanoma skin cancer compared to normal skin and adult keratinocytes

April 2018 in “Journal of Investigative Dermatology”

Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.

research Stem Cells in Nonmelanoma Skin Cancer

January 2004

Stem cells play a key role in nonmelanoma skin cancers, with different origins and genetic changes linked to basal and squamous cell carcinomas.

Association of Melanoma and Nonmelanoma Skin Cancer with Antihypertensive Drugs: A Report from the Research on Adverse Drug Events and Reports Project

research Association of melanoma and nonmelanoma skin cancer with antihypertensive drugs: A report from the Research on Adverse Drug events And Reports project

1 citations , April 2016 in “Journal of The American Academy of Dermatology”

Blood pressure medications may increase the risk of skin cancer.

research Association of Hypothyroidism With Nonmelanoma Skin Cancer in the Multiethnic Cohort Population-Based Study

September 2018 in “Dermatologic Surgery”

Hypothyroidism may increase the risk of nonmelanoma skin cancer.

research Defining and targeting differentiation of non-melanoma skin cancer

June 2014

Basal cell carcinoma behaves like hair follicles and targeting specific pathways may help treat it.

Rothmund-Thomson Syndrome With Late Onset and Effective Preventive Control of Non-Melanoma Cancer With Acitretin: Case Report

research Rothmund Thomson syndrome with late onset and good preventive control of non-melanoma cancer with acitretin: case report

August 2024 in “Journal of Dermatology & Cosmetology”

Acitretin effectively prevented skin cancer in a patient with late-onset Rothmund-Thomson syndrome.

research Pre‐clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer

36 citations , October 2019 in “Cell Proliferation”

Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.

research Prevalence and associated factors of skin cancer in aged nursing home residents: A multicenter prevalence study

14 citations , April 2019 in “PLOS ONE”

Skin cancer is common in elderly nursing home residents, with risk factors including being male, having light skin, outdoor work history, and smoking. Regular skin checks are recommended.

research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers

3 citations , June 2021 in “Clinical, Cosmetic and Investigational Dermatology”

Dermoscopy is an effective tool for accurately detecting skin cancers.

research Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers

7 citations , August 2022 in “Experimental dermatology”

Blocking YAP/TAZ could be a new way to treat skin cancer.

research H11 More cancer, better counting or better at diagnosis? The history of skin cancer registration

June 2023 in “British Journal of Dermatology”

High-quality data on skin cancer is crucial for understanding its trends and allocating healthcare resources effectively.

What Bothers You Most About Your Skin Cancer? 700 Patients Respond

research What is it about your skin cancer that bothers you the most? 700 patients respond

May 2014 in “Journal of The American Academy of Dermatology”

Patients with nonmelanoma skin cancers are most bothered by fear of progression, appearance concerns, and having cancer.

research Estrogens and aging skin

150 citations , April 2013 in “Dermato-endocrinology”

Estrogen therapy can reduce skin aging but has cancer risks.

research Field Cancerization: From Molecular Basis to Selective Field-Directed Management of Actinic Keratosis

27 citations , December 2014 in “Current problems in dermatology”

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

research Skin health of community-living older people: a scoping review

12 citations , June 2024 in “Archives of Dermatological Research”

Older people at home often have skin issues, but there's little evidence on how to prevent or treat them effectively.

Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to Age Groups: A Retrospective Observational Study

research Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to the Age Groups: A Retrospective Observational Study

June 2023 in “Life”

Melanoma characteristics vary by age, which could help doctors with diagnosis and prevention.

research Cancer risk in patients with alopecia areata: a nationwide population‐based matched cohort study

15 citations , March 2018 in “Cancer Medicine”

Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.

Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Near the Distal End of the Arrector Pili Muscle

research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle

5 citations , January 2016 in “Stem Cells International”

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

research Skin Stem Cells: At the Frontier Between the Laboratory and Clinical Practice. Part 1: Epidermal Stem Cells

2 citations , November 2015 in “Actas Dermo-Sifiliográficas”

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

research Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients

March 2023

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

research Beta Human Papillomavirus and Merkel Cell Polyomavirus in Skin Neoplasms

2 citations , April 2020 in “International Journal of Dermatology and Venereology”

Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.

research Genome-wide association study of skin complex diseases

25 citations , March 2012 in “Journal of Dermatological Science”

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

research Review article: dermatological complications of immunosuppressive and anti-TNF therapy in inflammatory bowel disease

60 citations , September 2013 in “Alimentary Pharmacology & Therapeutics”

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Dermoscopy of Scalp Tumors: A Multi-Center Study Conducted by the International Dermoscopy Society

research Dermoscopy of scalp tumours: a multi‐centre study conducted by the international dermoscopy society

34 citations , July 2011 in “Journal of the European Academy of Dermatology and Venereology”

The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.