18 citations
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July 2020 in “Basic and Clinical Andrology” Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
5 citations
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January 2018 in “Research Journal of Pharmacy and Technology” Finasteride significantly reduces fertility in male rats.
March 2014 in “Fertility and Sterility” The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
37 citations
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January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
Minoxidil may harm male reproductive health by causing testicular damage and hormonal disruption.
April 2016 in “The FASEB Journal” Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.
January 2023 in “Andrologia” American men are older, more obese, and have longer infertility than Canadian men.
7 citations
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April 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
December 2023 in “Benha Journal of Applied Sciences” Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.
13 citations
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June 2008 in “Springer eBooks” January 2019 in “Indian Journal of Dermatology, Venereology and Leprology”
1 citations
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September 2019 in “Steroids” Two new mutations in the AR gene linked to severe androgen insensitivity were found.
7 citations
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September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
2 citations
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September 2008 in “Fertility and Sterility” Adult offspring of sperm donation generally feel positive about their conception and view the donor as their biological father.
3 citations
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October 2011 in “JAT. Journal of applied toxicology/Journal of applied toxicology” Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
34 citations
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January 2004 in “PubMed” DHT deficiency in rats reduces sperm content and affects testis structure over time.
5 citations
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March 2005 in “Journal of The American Academy of Dermatology”
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.
53 citations
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January 1986 in “Endocrinology” Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
25 citations
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January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
21 citations
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December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
1 citations
,
August 2019 in “Journal of pediatric & adolescent gynecology” A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
September 2024 in “Journal of the American Academy of Dermatology” Early-onset male baldness may increase the risk of metabolic syndrome.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” Certain fats in the blood are linked to an increased risk of male pattern baldness.
Finasteride causes reproductive malformations in male rats.
54 citations
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November 1995 in “The Journal of Clinical Endocrinology & Metabolism” Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
15 citations
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September 2014 in “JAMA Dermatology”
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
Finasteride causes reproductive changes in male rats.
20 citations
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March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.