research A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome
A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.
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research Investigation of four novel male androgenetic alopecia susceptibility loci: no association with female pattern hair loss
No link found between new male baldness genes and female hair loss.
research Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride
A new method was developed to purify finasteride for better medical use.
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
research 13C-NMR study of 4-azasteroids in solution and solid state
4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.
research Allelic frequencies for the seventeen Y-STR loci observed in Iraqi male patients with prostate cancer
Certain genetic markers on the Y-chromosome may influence prostate cancer risk in Iraqi males.
research The impact of minoxidil on male reproductive biology: a multi-approach study including systematic review, in vivo, and ex vivo experiments
Minoxidil may harm male reproductive health by causing testicular damage and hormonal disruption.
research What should it take to describe a substance or product as 'sperm-safe'
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Morphology of the testis and the epididymis in rats with dihydrotestosterone (DHT) deficiency.
DHT deficiency in rats reduces sperm content and affects testis structure over time.
research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production
Omega-6 fats in certain cells boost male hormone production.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Finasteride in Young Men: Effects on Semen and Hormones?
Finasteride improves hair but may reduce sperm quality at higher doses.
research Single injection of very mild dose BOTOX in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice
A small BOTOX dose improved sperm production and movement in older mice.
research A pilot study of paternal drug exposure: the Motherisk experience
More research is needed on the safety of fathers' drug exposure before conception.
research Aromatase deficiency in a male patient - Case report and review of the literature.
A male with aromatase deficiency improved bone health with estradiol treatment.
research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research EFFECT OF LOW DOSE FINASTERIDE ON SEMEN VOLUME AND SPERM DENSITY IN YOUNG MEN
research Evaluation of Serum Level of Zinc Alpha 2 Glycoprotein in Male Patients with Androgenetic Alopecia
Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.
research Molecular basis of androgen insensitivity
Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
research Identification of two additional novel mutations in the AR gene associated with severe forms of androgen insensitivity syndrome
Two new mutations in the AR gene linked to severe androgen insensitivity were found.
research Geographical Differences in Male Infertility between the United States and Canada: Insights from the Andrology Research Consortium
American men are older, more obese, and have longer infertility than Canadian men.
research Lesson of the week: Haemochromatosis as an endocrine cause of subfertility
Haemochromatosis can cause infertility by affecting hormone glands.
research Azithromycin with nitazoxanide, hydroxychloroquine or ivermectin, with or without dutasteride, for early stage COVID-19: an open-label prospective observational study in males with mild-to-moderate COVID-19 (The Pre-AndroCoV Male Trial).
Men with male pattern baldness had worse COVID-19 symptoms, but early treatment with certain drugs improved outcomes for all.
research El finasteride como control positivo en estudios de reproducción
Finasteride causes reproductive changes in male rats.
research C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research Novel Androgen Receptor Gene Variant Containing a Premature Termination Codon in a Patient with Androgen Insensitivity Syndrome
A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
research The Effect of Perinatal Blockade of Androgen Receptors on the Expression of Hypothalamic Estrogen Receptor‐a and Sexual Motivation in Male Rats
Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.
research 46, XY 5-Alpha Reductase Deficiency in a 36-Year-Old Phenotypic Female Patient
A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.
research COVID-19 and andrology: Recommendations of the French-speaking society of andrology (Société d’Andrologie de langue Française SALF)
Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
research Anogenital distance as a biomarker for incomplete masculinization : Molecular mechanisms in the perineum
A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.