May 2025 in “International Journal of Women’s Dermatology” CCCA mainly affects Black women and is linked to high-tension hairstyles, heating tools, chemical relaxants, and genetics.
15 citations
,
February 2006 in “Journal of Investigative Dermatology” More research is needed to understand and treat cicatricial alopecias.
1 citations
,
June 2022 in “PubMed” Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.
18 citations
,
October 2012 in “Dermatologic Clinics” Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
2 citations
,
May 2020 in “Journal of the American Academy of Dermatology” Hair shaft changes may be linked to CCCA, but their role is unclear.
17 citations
,
August 2004 in “International Journal of Dermatology” Prolonged pressure on the scalp can cause permanent hair loss.
19 citations
,
July 2022 in “PNAS Nexus” Similar treatments might work for different types of scarring hair loss.
November 2024 in “Journal of Investigative Dermatology” Genetic changes in specific proteins contribute to hair loss in some women of African descent.
42 citations
,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
19 citations
,
August 2011 in “Archives of Dermatology” CCCA is a common scarring hair loss in African descent women, possibly linked to genetics, hair care practices, and health issues like diabetes.
32 citations
,
March 2008 in “SKINmed Dermatology for the Clinician” Accurate diagnosis and tailored treatment are crucial for managing complex hair loss conditions.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
21 citations
,
February 2009 in “Journal of the American Academy of Dermatology” Some cases of tinea capitis, a fungal scalp infection, can look like scarring hair loss due to the body's immune response and the fungus itself.
March 2026 in “Journal of Investigative Dermatology” Genetic factors, especially PADI3 gene variants, contribute to CCCA in women of African descent.
1 citations
,
June 2012 in “Actas Dermo-Sifiliográficas” Early and aggressive treatment of scarring alopecia is important to prevent further hair follicle damage.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.
September 2019 in “Journal of Investigative Dermatology” CCCA in women of African ancestry may be caused by PADI3 gene mutations and intense hair grooming.
September 2024 in “Portuguese Journal of Dermatology and Venereology” CCCA and LPP may be related hair loss conditions influenced by genetics and environment, needing early treatment.
March 2004 in “Journal of the American Academy of Dermatology” Middle-aged women with cicatricial alopecia/lichen planopilaris responded well to treatments like ketoconazole shampoo and steroids.
15 citations
,
November 1998 in “Australasian Journal of Dermatology” Cicatricial pemphigoid rarely affects the scalp but is hard to treat when it does.
July 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Early diagnosis and treatment can lessen the impact of cicatricial alopecia.
1 citations
,
April 2019 in “Journal of Investigative Dermatology” Oral minoxidil can potentially increase hair growth in people suffering from Central Centrifugal Cicatricial Alopecia.
98 citations
,
May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
1 citations
,
May 2022 in “Dermatologic Therapy” Hair transplants can be used for rare types of scarring hair loss.
2 citations
,
June 2012 in “PubMed” The document concludes that central centrifugal cicatricial alopecia (CCCA) should be considered in African American men with vertex hair loss and scalp symptoms, and that prompt diagnosis and treatment can slow disease progression.
September 2025 in “Surgeries” Hair transplants can work for stable cicatricial alopecia, but success varies by condition.
February 2024 in “International journal of medical science and clinical research studies” CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.
January 2020 in “JAAD case reports” Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
1 citations
,
December 2022 in “Research Square (Research Square)” Certain health conditions and hair care habits affect the treatment results for a scalp condition called Central Centrifugal Cicatricial Alopecia.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."