research Cortisol determination in hair and faeces from domestic cats and dogs
Hair cortisol can reliably indicate chronic stress in cats and dogs.
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research Production of ultraviolet-light-induced skin erythema in the hairless rat: a comparison with the haired rat in screening for anti-inflammatory drugs
Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.
research AnnoPharma: Detection of substances responsible of ADR by annotating and extracting information from MEDLINE abstracts
AnnoPharma effectively identifies substances causing adverse drug reactions in medical abstracts.
research Where it all went right
Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.
research Hepatic and renal impairment and degenerative changes caused by carbon black nanoparticles in mice
Carbon black nanoparticles can harm liver and kidney function in mice.
research Reporting on Adverse Clinical Events
Different medications can cause serious side effects in some people.
research Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats"
research Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats"
research P22-023-23 Pilot Study Protocol on Application of Non-Invasive Vitamin D Hair Test and Screening E-Tool for Indigenous Populations in the Great Northern Plains
research Sexual adverse events-related to dutasteride e finasteride: analysis of real-life data from Eudra-Vigilance database
research Repurposing of approved cardiovascular drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control
Epristeride's metabolism in zebrafish helps improve doping detection methods.
research Subjects with mild alopecia benefit from aminexil clinical 5: results of a large international observational study
Aminexil clinical 5 effectively reduces hair loss and is well-tolerated.
research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research Evaluation of the safety and effectiveness of intradermal administration of QR678 Neo® hair growth factor formulation: A phase‐IV, open‐label, single‐arm multi‐ethnicity clinical trial
QR678 Neo® is a safe and effective treatment for hair loss in men and women.
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Pathological Insights into the Limitations of Clinical and Dermoscopic Evaluations in Monitoring Sonidegib Treatment Response for Locally Advanced Basal Cell Carcinoma: A Real-World Study
Sonidegib is effective and safe for treating advanced basal cell carcinoma, but biopsies are needed to confirm tumor clearance.
research Metabolism of Minoxidil, a New Hypotensive Agent 11: Biotransformation following Oral Administration to Rats, Dogs, and Monkeys
Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
research Isolation and structural identification of a novel minoxidil analogue in an illegal dietary supplement: triaminodil
A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
research Comment on “Low dose oral minoxidil for treating alopecia: A 3-year North American retrospective case series”: Adding further evidence about side effects
Low-dose oral minoxidil for hair loss seems to have rare side effects, but more research is needed to confirm its safety.
research Application of 2-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazol (NBDCL) for Spectrophotometric Determination of Finasteride in Pharmaceutical Formulation
A new method using NBD-CL can accurately and precisely measure finasteride in medicine, and could be used regularly for quality control in the industry.
research Post-Drug Syndromes: A Neglected Challenge in Pharmacovigilance and Public Health
Current drug safety systems fail to detect long-term side effects, leading to preventable health issues.
research Summary of an Audit of Clinical Trial Studies Conducted in the United States, Europe, Canada, and Australia for the Treatment of Various Types of Alopecia Over a Six-Year Period
The document's conclusion cannot be provided because the content is not available.
research Clinical Trial of Finasteride on Alopecia X in a Dog
research A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research ALLETHRIN INDUCED TOXICOPATHOLOGICAL ALTERATIONS IN ADULT MALE ALBINO RATS
Allethrin caused harmful effects and organ damage in rats, worsening with higher doses and longer exposure.
research Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice
Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
research Development of an aequorin-based assay for the screening of corticotropin-releasing factor receptor antagonists
The new assay can help develop products for hair re-growth.
research Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.
TCDD reduces EGF receptor activity and causes various developmental changes in animals.